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81. Can 4-nonylphenol induce vitellogenin-like
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82. Antiandrogenic activity of pyrethroid
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83. Titanium dioxide mediated photocatalytic
 
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84. Poison earth, poison woman: making
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85. Circulating thyroid hormone levels
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86. Kinetics of n-butyl benzyl phthalate
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87. Aerobic degradation of diethyl
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88. Structure-based classification
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89. DDT serum concentration and menstruation
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90. Exposure of young men to organochlorine
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91. Bisphenol A-recognition polymers
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92. Organochlorine levels in adipose
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93. Vitellogenin gene expression in
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94. Linking molecular interactions
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95. Organochlorine levels in adipose
 
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96. Developmental exposure to environmental
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97. A study of the preparation and
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98. Sensitivity of expression of perivitelline
 
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99. Di(2-ethylhexyl) phthalate metabolites
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100. Seasonal flux of nonylphenol in

81. Can 4-nonylphenol induce vitellogenin-like proteins in the clam Tapes philippinarum? [An article from: Environmental Research]
by V. Matozzo, M.G. Marin
Digital: Pages (2005-01-01)
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Asin: B000RR3NXC
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Editorial Review

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This digital document is a journal article from Environmental Research, published by Elsevier in 2005. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
Vitellogenins (Vg) are precursors of egg-yolk proteins (vitellins) constituting energy reserves for embryos. In oviparous females, Vg are produced in the liver (or equivalent organs) under the control of endogenous estrogens, released into the bloodstream (plasma or hemolymph), and stored in developing oocytes. Although Vg levels are generally undetectable in male plasma, they may significantly increase in (xeno-)estrogen-exposed males. The aim of the present study was to evaluate estrogenic effects of 4-nonylphenol (NP) in sexually differentiated males and females of the Manila clam Tapes philippinarum. Clams were exposed for 7 days to various sublethal NP concentrations (0, 0+acetone, 0.025, 0.05, 0.1, and 0.2mg NP/L) and Vg-like protein levels were evaluated in both hemolymph and digestive glands of mollusks by the alkali-labile phosphate assay. This method, based on the determination of phosphates released by Vg, has previously been used to detect Vg concentrations in both fish plasma and bivalve hemolymph. Although Vg levels were generally higher in both hemolymph and digestive gland of T. philippinarum females, males appeared to be more sensitive than females to the estrogenic effects of NP. In males exposed to 0.1 and 0.2mg NP/L, Vg levels increased significantly in both hemolymph (P<0.05 and P<0.01, respectively) and digestive gland (P<0.05), whereas no changes were observed in those of females. Although the mechanisms by which NP exerts its in vivo endocrine-modulating effects in bivalve mollusks remain unclear, the results of this study demonstrate that NP may induce Vg-like proteins in T. philippinarum, particularly males. ... Read more


82. Antiandrogenic activity of pyrethroid pesticides and their metabolite in reporter gene assay [An article from: Chemosphere]
by H. Sun, X.L. Xu, L.C. Xu, L. Song, X. Hong, Chen
Digital: Pages (2007-01-01)
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Asin: B000PC0G2U
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This digital document is a journal article from Chemosphere, published by Elsevier in 2007. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

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Many pesticides possess hormonal activity and have thus been classified as endocrine disruptors. Pyrethroids are commonly used pesticides worldwide, but little has been done to characterize their antiandrogenic activity potential. We tested three frequently encountered pyrethroids (fenvalerate, cypermethrin, permethrin) and their metabolite 3-phenoxybenzoic acid (3-PBA) for antiandrogenic and androgenic activity using a human androgen receptor (AR) mediated luciferase reporter gene assay in CV-1 African green monkey kidney cell. The assay displayed appropriate response to the known AR agonist 5@a-dihydrotestosterone and AR antagonist nilutamide and flutamide. At 0.1mM, all the three tested pyrethroids significantly suppressed the luciferase expression. Further, their metabolite 3-PBA also showed antagonist activity. None of the test chemicals showed androgenic activity. Through the antiandrogenic pathways, exposure to certain pyrethroids may contribute to the damage of reproductive system. In conclusion, pyrethroid pesticides can act as antiandrogen in vitro, and metabolizing to 3-PBA cannot eliminate the antagonist activity. This result provides useful information for risk assessment of pyrethroid pesticides. ... Read more


83. Titanium dioxide mediated photocatalytic degradation of dibutyl phthalate in aqueous solution-kinetics, mineralization and reaction mechanism [An article from: Chemical Engineering Journal]
by S. Kaneco, H. Katsumata, T. Suzuki, K. Ohta
Digital: Pages (2006-12-01)
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Asin: B000PC04OK
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This digital document is a journal article from Chemical Engineering Journal, published by Elsevier in 2006. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

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The photocatalyzed degradation conditions of di-n-butyl-ortho-phthalate, a representative endocrine disruptor, in aqueous titanium dioxide (TiO"2)-suspended solution were optimized. The effect of various factors, such as photocatalyst dosage, initial substrate concentration, temperature, pH and co-existing organic substance, on the photocatalytic degradation of dibutyl phthalate was investigated. The final mineralization product was carbon dioxide during the degradation of dibutyl phthalate in aqueous solution. The intermediate products were identified by GC-MS technique. On the basis of the detected intermediate species and the calculated frontier electron densities of dibutyl phthalate structure, the photocatalytic degradation reaction pathways were proposed. The photocatalytic degradation treatment for the wastewater including phthalic acid esters is simple, easy handling and low cost. ... Read more


84. Poison earth, poison woman: making the connection.(young FEMINISTS): An article from: Women's Health Activist
by Alison Ojanen-Goldsmith
 Digital: 5 Pages (2009-07-01)
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Asin: B002F1RCT4
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This digital document is an article from Women's Health Activist, published by National Women's Health Network on July 1, 2009. The length of the article is 1383 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available immediately after purchase. You can view it with any web browser.

Citation Details
Title: Poison earth, poison woman: making the connection.(young FEMINISTS)
Author: Alison Ojanen-Goldsmith
Publication: Women's Health Activist (Magazine/Journal)
Date: July 1, 2009
Publisher: National Women's Health Network
Volume: 34Issue: 4Page: 8(2)

Distributed by Gale, a part of Cengage Learning ... Read more


85. Circulating thyroid hormone levels and iodothyronine deiodinase activities in Nile tilapia (Oreochromis niloticus) following dietary exposure to Endosulfan ... Biochemistry and Physiology, Part C]
by A.M. Coimbra, M.A. Reis-Henriques, V.M. Darras
Digital: Pages (2005-05-01)
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Asin: B000RR37TM
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This digital document is a journal article from Comparative Biochemistry and Physiology, Part C, published by Elsevier in 2005. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

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We evaluated the effects of two organochlorinated environmental contaminants, Endosulfan and Aroclor 1254 on peripheral thyroid hormone metabolism and thyroid hormone plasma levels in Nile tilapia (Oreochromis niloticus). Tilapia were exposed through diet to 0.1 and 0.5 @mg g^-^1 of Endosulfan and 0.5 @mg g^-^1 of Aroclor 1254 for 21 and 35 days. Decreased plasma T4 and rT3 levels were observed in tilapia exposed to the lower dose of Endosulfan, while treatment with a higher dose and Aroclor 1254 produced no changes. Plasma T3 levels were not affected by these compounds. Hepatic type I deiodinase (D1) activity was depressed by a lower dose of Endosulfan and hepatic type III (D3) activity was increased following 35 days of exposure to the lower dose of Endosulfan and following 21 and 35 days of exposure to Aroclor 1254; while type II (D2) remained unchanged in liver as well as in all other organs analysed. Apart from hepatic D3 activity, Endosulfan and Aroclor 1254 also increased D3 activity in gill, but not in other tested organs. It is concluded that dietary exposure of tilapia to Endosulfan or Aroclor 1254 can lead to changes in circulating thyroid hormone levels and/or in peripheral thyroid hormone metabolism. The changes in hormone metabolism differ between tissues, eventually reflecting tissue-specific differences in adaptation. ... Read more


86. Kinetics of n-butyl benzyl phthalate degradation by a pure bacterial culture from the mangrove sediment [An article from: Journal of Hazardous Materials]
by X.R. Xu, H.B. Li, J.D. Gu, X.Y. Li
Digital: Pages (2007-02-09)
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Asin: B000PDSRAW
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This digital document is a journal article from Journal of Hazardous Materials, published by Elsevier in 2007. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

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n-Butyl benzyl phthalate (BBP) is an endocrine-disrupting chemical. Biodegradation of BBP by a bacterium, Pseudomonas fluorescens B-1, isolated from the mangrove sediment, was investigated. The microorganism can utilize BBP as the sole carbon and energy source, where concentrations of BBP disappeared within 6 days under shake culture conditions. Effects of BBP concentration, pH, temperature, and salinity on BBP biodegradation were studied, respectively. The process of BBP biodegradation was monitored by reversed-phase high-performance liquid chromatography with ultra-violet detection after solid-phase extraction. The biodegradation of BBP could be fitted to a first-order kinetic model. The major metabolites of BBP degradation were identified as mono-butyl phthalate, mono-benzyl phthalate, phthalic acid and benzoic acid by gas chromatography-mass spectrometry, and a preliminary metabolic pathway of BBP was proposed. ... Read more


87. Aerobic degradation of diethyl phthalate by Sphingomonas sp. [An article from: Bioresource Technology]
by H.H.P. Fang, D. Liang, T. Zhang
Digital: Pages (2007-02-01)
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Asin: B000PAU80M
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This digital document is a journal article from Bioresource Technology, published by Elsevier in 2007. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

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An aerobic diethyl phthalate (DEP) degrading bacterium, DEP-AD1, was isolated from activated sludge. Based on its 16S rDNA sequence, this isolate was identified belonging to Sphingomonas genus with 99% similarity to Sphingomonas sp. strain C28242 and 98% similarity to S. capsulate. The specific degradation rate of DEP was concentration dependent with a maximum of 14mg-DEP/(Lh). Results of degradation tests showed that DEP-AD1 could also degrade monoethyl phthalate (MEP), dimethyl phthalate (DMP), dibutyl phthalate (DBP), and diethylhexyl phthalate (DEHP), but not phthalate and benzoate. ... Read more


88. Structure-based classification of active and inactive estrogenic compounds by decision tree, LVQ and kNN methods [An article from: Chemosphere]
by A. Asikainen, M. Kolehmainen, J. Ruuskanen, Tuppur
Digital: Pages
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This digital document is a journal article from Chemosphere, published by Elsevier in . The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

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The performance of decision tree (DT), learning vector quantization (LVQ), and k-nearest neighbour (kNN) methods classifying active and inactive estrogenic compounds in terms of their structure activity relationship (SAR) was evaluated. A set of 311 compounds was used for construction of the models, the predictive power of which was verified with separate training and test sets. Principal components derived from molecular descriptors calculated with DRAGON software were used as variables representing the structures of the compounds. Broadly, kNN had the best classification ability and DT the weakest, although the performance of each method was dependent on the group of compounds used for modelling. The best performance was obtained with kNN for the calf estrogen receptor data, averaging 98.3% of correctly classified compounds in the external tests. Overall, the results indicate that all the methods tested are suitable for the SAR classification of estrogenic compounds, producing models with a predictive power ranging from adequate to excellent. ... Read more


89. DDT serum concentration and menstruation among young Chinese women [An article from: Environmental Research]
by A. Chen, J. Zhang, L. Zhou, E.s. Gao, L. Chen, Rog
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Asin: B000RR76GM
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This digital document is a journal article from Environmental Research, published by Elsevier in . The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

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High DDE and DDT concentrations were found to be associated with shortened menstrual cycle length in Laotian immigrants to the United States. We examined this issue in a sample of young Chinese women. A total of 60 women aged 20-24 years were enrolled in three maternal and child health clinics (20 from urban, 20 from suburban, 20 from rural) in Shanghai, China, and vicinity, in 1998. Of these women, 47 who did not use hormonal contraceptives and had valid menstrual cycle characteristics were included in the analysis for associations among serum DDE and DDT concentration and menstrual cycle length, duration of menses, and heaviness of menstrual flow. In univariate analysis, higher p,p'-DDE concentration was associated with longer menstrual cycle length (0.66 day per 10@mg/L, 95% confidence interval [CI]: 0.21, 1.11 day). With adjustment for age, body mass index, education, occupation, and resident location, the estimate was 0.42 day (95% CI: -0.35, 1.19 day). p,p'-DDE was not associated with duration of menses or heaviness of menstrual flow. Neither p,p'-DDT nor o,p'-DDT were associated with menstrual cycle length, duration of menses or heaviness of menstrual flow. The study largely suggests no association between DDE and DDT concentrations and menstrual cycle characteristics in young Chinese women, though the weak-to-no correlation of DDE with menstrual cycle length merits further study. ... Read more


90. Exposure of young men to organochlorine pesticides in Southern Spain [An article from: Environmental Research]
by J. Carreno, A. Rivas, A. Granada, Jose Lopez-Espin
Digital: 6 Pages (2007-01-01)
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Asin: B000PC6LBA
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This digital document is a journal article from Environmental Research, published by Elsevier in 2007. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

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It has been hypothesized that endocrine disruptors and especially synthetic estrogenic environmental contaminants (xenoestrogens) are etiologic factors in the global decrease of sperm counts and other problems of the male reproductive tract, including cryptorchidism, hypospadias, and testicular cancer. This possibility has prompted research into the current and historical incidence of these diseases. The largest area of intensive greenhouse agriculture in Europe is near the Mediterranean coast of Southern Spain, where this activity has greatly expanded since the 1960s. We determined and compared levels of 14 organochlorine pesticides in the blood of 220 young males in Southern Spain. Aldrin, dieldrin, endrin, lindane, methoxychlor, endosulfans, and DDT and its metabolites were identified. Detectable concentrations of p,p'-DDE were found in 96% of serum samples. Among the remaining DDTs, o,p'-DDD was the most prevalent, detected in 65% of serum samples. Detectable concentrations of endosulfan I or II or their metabolites endosulfan-diol, or -sulfate were found in all samples; endosulfan-diol was the most frequently detected metabolite (92%) followed by sulfate. Results indicate that men of reproductive age in Southern Spain have been and are exposed to organochlorine pesticides. Because many of these chemicals have estrogenic and anti-androgenic activity, further research is warranted to interpret the male reproductive health consequences of this exposure. ... Read more


91. Bisphenol A-recognition polymers prepared by covalent molecular imprinting [An article from: Analytica Chimica Acta]
by T. Ikegami, T. Mukawa, H. Nariai, T. Takeuchi
Digital: Pages (2004-02-16)
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Asin: B000RR00EC
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This digital document is a journal article from Analytica Chimica Acta, published by Elsevier in 2004. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

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A specific recognition material for bisphenol A (BPA) was prepared by using a covalent imprinting technique. A chloroform solution containing bisphenol A dimethacrylate as a template, ethylene glycol dimethacrylate as a cross-linking agent and 2,2'-azobis(isobutyronitrile) as an initiator was polymerized by UV initiation. When BPA was removed from the resulting polymer by hydrolysis of the ester bonds with aqueous sodium hydroxide, carboxylic acid residues were generated in the polymer. After the polymer was packed into a stainless steel column, retention factors of BPA and related compounds were measured. The imprinted polymer adsorbed BPA and structurally related compounds such as 4,4'-dihydroxybenzophenone, bis(4-hydroxyphenyl)sulfone and 4,4'-dihydroxybiphenyl. A typical association constant (K"a) was calculated to be 1.72x10^5M^-^1 by Scatchard analysis. Interestingly, 17@a- and 17@b-estradiol were also bound to the imprinted polymer (K"a=1.68x10^5M^-^1), indicating that the polymer could be used as artificial receptors for screening the compounds having estrogenic action. ... Read more


92. Organochlorine levels in adipose tissue of women from a littoral region of Argentina [An article from: Environmental Research]
by M. Munoz-de-Toro, H.R. Beldomenico, S.R. Garcia
Digital: 5 Pages (2006-09-01)
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Asin: B000PAA640
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This digital document is a journal article from Environmental Research, published by Elsevier in 2006. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

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Organochlorine compounds (OCCs), such as pesticides and polychlorinated biphenyls (PCBs), are persistent lipophilic chemicals identified as endocrine disruptors, mainly with estrogen-like effects. Northeastern Argentina, near the Parana River, is characterized by intensive farming and agricultural activities and industrial development, and is therefore prone to high incidences of environmental and dietary exposure to OCCs. Hence, we conducted a study to (1) estimate the organochlorine residues present in mammary fat tissue in a population of women from this littoral region and (2) identify potential sources of exposure to OCCs. Our subjects were 76 women (residing in and around Santa Fe city and not occupationally exposed to organochlorines) who underwent excision biopsy of a breast lesion or had plastic surgery. Both frequency of occurrence and levels of organochlorine residues were high in breast adipose tissue of all the participants. The organochlorine residues most frequently found were p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) in all the subjects analyzed, hexachlorobenzene (HCB) in 86.8%, and @b-hexachlorocyclohexane (@b-HCH) in 75.0%. The incidence of PCB congeners was very low. p,p'-DDE and @b-HCH residues reached the highest levels, 4794 and 1780ppb, respectively. The diet was a relevant source of exposure, consumption of animal fat and freshwater fish playing a significant role. Bioaccumulation was evidenced by the significant positive association between organochlorine levels and body mass index (p=0.0003) and the age of the patient (p=0.0002). The frequency and levels of OCCs found in our study population raise concerns regarding Argentinean exposure to these endocrine disruptors. ... Read more


93. Vitellogenin gene expression in males of the Antarctic fish Trematomus bernacchii from Terra Nova Bay (Ross Sea): A role for environmental cadmium? [An article from: Chemosphere]
by A. Canapa, M. Barucca, S. Gorbi, M. Benedetti, Zuc
Digital: Pages (2007-01-01)
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Asin: B000PC0MXI
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This digital document is a journal article from Chemosphere, published by Elsevier in 2007. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

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Synthesis of vitellogenin (VTG) in male fish is a widely recognized effect for estrogenic pollutants in temperate environments, while similar investigations are still lacking for Antarctic organisms. In this study, a preliminary characterization of vitellogenin gene expression was performed by RT-PCR in the key species Trematomus bernacchii sampled in different phases of reproductive cycle and food availability. Females exhibited the highest gene expression during the spawning period, but VTG mRNA was always detected also in males; a significant increase of gene expression was observed both in males and females at the end of the feeding season. These results were not fully supported by a differential exposure to phyto- or anthropogenic estrogens during the planctonic cycle; on the other side, the endocrine properties of cadmium, naturally elevated in Terra Nova Bay and increasing during algal bloom, would explain both the presence of VTG mRNA in males and the seasonal changes of gene induction. Laboratory exposures did not reveal short-term estrogenic effects of cadmium while an elevated responsiveness of T. bernacchii was observed toward a classical estrogenic receptor agonist (17@b-estradiol). Different hypotheses were considered to suggest delayed endocrine effects of cadmium, including the early interaction with other cellular detoxification systems or alterations at multiple levels of the hypothalamus-pituitary-gonad-liver axis. Although molecular mechanisms of VTG gene expression in males of T. bernacchii remain unclear, obtained results provide interesting insights on this species which should stimulate future research activities. ... Read more


94. Linking molecular interactions to consequent effects of persistent organic pollutants (POPs) upon populations [An article from: Chemosphere]
by P. Vasseur, C. Cossu-Leguille
Digital: Pages
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This digital document is a journal article from Chemosphere, published by Elsevier in . The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

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There is great concern about the potential adverse effects of persistent organic pollutants (POPs) on wildlife. Threats come from toxic chemicals with long half lives in the environment that were released worldwide on a large scale in the past, at a time when little was known of their potential effects on the environment. Although the Stockholm Convention (2001) initially targeted 12 POP chemicals-organochlorinated compounds-for the reduction/elimination of releases, the problem can be extended to persistent toxic substances more generally. Therefore, identifying early biomarkers for possible toxic effects to populations in the long term is a challenge for ecotoxicologists. Regional decline in fish, bird and/or invertebrate populations resulting from exposure to POPs, such as DDT (dichlorodiphenyltrichloroethane), PCBs (polychlorinated biphenyls), PCDD (polychlorinated dibenzo-p-dioxins), and TBT (tributyltin) could be related to some biochemical, endocrine and physiological effects in individuals. Examples of known mechanisms of POP ecotoxicity will be illustrated in the first part. The next parts will be devoted to (i) data gaps and limitations to extrapolation from lower to higher levels of biological organization, (ii) confusing factors in field studies and the combined effects of persistent toxic pollutants and (iii) recommendations for the design and interpretation of experimental studies. ... Read more


95. Organochlorine levels in adipose tissue of women from a littoral region [An article from: Environmental Research]
by M. Munoz-de-Toro, H.R. Beldomenico, S.R. Garcia
Digital: 5 Pages (2006-09-01)
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Asin: B000P6OFKU
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Editorial Review

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This digital document is a journal article from Environmental Research, published by Elsevier in 2006. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
Organochlorine compounds (OCCs), such as pesticides and polychlorinated biphenyls (PCBs), are persistent lipophilic chemicals identified as endocrine disruptors, mainly with estrogen-like effects. Northeastern Argentina, near the Parana River, is characterized by intensive farming and agricultural activities and industrial development, and is therefore prone to high incidences of environmental and dietary exposure to OCCs. Hence, we conducted a study to (1) estimate the organochlorine residues present in mammary fat tissue in a population of women from this littoral region and (2) identify potential sources of exposure to OCCs. Our subjects were 76 women (residing in and around Santa Fe city and not occupationally exposed to organochlorines) who underwent excision biopsy of a breast lesion or had plastic surgery. Both frequency of occurrence and levels of organochlorine residues were high in breast adipose tissue of all the participants. The organochlorine residues most frequently found were p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) in all the subjects analyzed, hexachlorobenzene (HCB) in 86.8%, and @b-hexachlorocyclohexane (@b-HCH) in 75.0%. The incidence of PCB congeners was very low. p,p'-DDE and @b-HCH residues reached the highest levels, 4794 and 1780ppb, respectively. The diet was a relevant source of exposure, consumption of animal fat and freshwater fish playing a significant role. Bioaccumulation was evidenced by the significant positive association between organochlorine levels and body mass index (p=0.0003) and the age of the patient (p=0.0002). The frequency and levels of OCCs found in our study population raise concerns regarding Argentinean exposure to these endocrine disruptors. ... Read more


96. Developmental exposure to environmental estrogens alters anxiety and spatial memory in female mice [An article from: Hormones and Behavior]
by B.C. Ryan, J.G. Vandenbergh
 Digital: 8 Pages (2006-06-01)
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Asin: B000P6OK4Q
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This digital document is a journal article from Hormones and Behavior, published by Elsevier in 2006. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

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Humans and wildlife are exposed to numerous anthropogenic drugs and pollutants. Many of these compounds are hormonally active, and recent evidence suggests that the presence of these endocrine disruptors permanently alters normal development and physiology in a variety of vertebrate species. Here, we report on the effects of developmental exposure to two common estrogenic pollutants, bisphenol A and ethinyl estradiol on sexually dimorphic, non-reproductive behavior. Mice (Mus musculus domesticus) were exposed to environmentally relevant levels of these chemicals (2 and 200 @mg/kg/day for bisphenol A and 5 @mg/kg/day for ethinyl estradiol) throughout prenatal and early postnatal development. As adults, the animals were observed in a variety of tests measuring sexually dimorphic behaviors including short-term spatial memory (in a radial-arm maze and a Barnes maze) and anxiety (in an elevated-plus maze and a light/dark preference chamber). Developmental exposure to ethinyl estradiol was found to masculinize behavior in all of the assays used. Bisphenol A increased anxious behavior in a dose-dependent fashion but had no effect on spatial memory. These results indicate that non-reproductive, sexually dimorphic behavior is sensitive to endocrine disruption. In addition, these experiments suggest that both humans and wildlife are being exposed to levels of these endocrine disrupting compounds that are sufficient to disrupt the development of the nervous system and that may have permanent consequences on sexually dimorphic behaviors. ... Read more


97. A study of the preparation and reactivity of potassium ferrate [An article from: Chemosphere]
by C. Li, X.Z. Li, N. Graham
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This digital document is a journal article from Chemosphere, published by Elsevier in . The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

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In the context of water treatment, the ferrate ([FeO"4]^2^-) ion has long been known for its strong oxidizing power and for producing a coagulant from its reduced form (i.e. Fe(III)). However, it has not been studied extensively owing to difficulties with its preparation and its instability in water. This paper describes an improved procedure for preparing solid phase potassium ferrate of high purity (99%) and with a high yield (50-70%). The characteristics of solid potassium ferrate were investigated and from XRD spectra it was found that samples of the solid have a tetrahedral structure with a space group of D"2"h (Pnma) and a=7.705A, b=5.863A, and c=10.36A. The aqueous stability of potassium ferrate at various pH values and different concentrations was investigated. It was found that potassium ferrate solution had a maximum stability at pH 9-10 and that ferrate solution at low concentration (0.25mM) was more stable than at high concentration (0.51mM). The aqueous reaction of ferrate with bisphenol A (BPA), a known endocrine disrupter compound, was also investigated with a molar ratio of Fe(VI):BPA in the range of 1:1-5:1. The optimal pH for BPA degradation was 9.4, and at this pH and a Fe(VI):BPA molar ratio of 5:1, approximately 90% of the BPA was degraded after 60s. ... Read more


98. Sensitivity of expression of perivitelline membrane glycoprotein ZP1 mRNA in the liver of Japanese quail (Coturnix japonica) to estrogenic compounds [An ... Biochemistry and Physiology, Part C]
by A.M. Hanafy, T. Sasanami, M. Mori
Digital: Pages (2007-01-01)
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Asin: B000PDT1R0
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Product Description
This digital document is a journal article from Comparative Biochemistry and Physiology, Part C, published by Elsevier in 2007. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
Avian perivitelline membrane protein, ZP1, is synthesized and secreted by the liver with the stimulation of estrogens. In the present study, we measured the expression of ZP1 gene in the liver of immature male quail treated with various estrogenic compounds and in the liver of male quail embryos that were developed in the fertilized eggs laid by mother quail injected with various estrogenic compounds during vitellogenesis. Total RNA extracted from the liver was reverse-transcribed and cDNA was subjected to real-time PCR. Both diethylstilbestrol and ethinyl estradiol caused significant effect on the increase in mRNA in immature male quail. In contrast, diethylstilbestrol administered via the route of maternal injection was not effective for induction of embryonic mRNA, although the effect of ethinyl estradiol administered via the same route was prominent. These results showed that direct administration of estrogenic compounds, diethylstilbestrol and ethinyl estradiol, stimulates the induction of ZP1 gene, but the rate of accumulation of these compounds in the yolk is different during vitellogenesis. The present studies suggest that although ZP1 gene is a sensitive biomarker to evaluate the effects of endocrine disruptors, the route of administration is an important factor to compare the effectiveness. ... Read more


99. Di(2-ethylhexyl) phthalate metabolites may alter thyroid hormone levels in men.(Research): An article from: Environmental Health Perspectives
by John D. Meeker, Antonia M. Calafat, Russ Hauser
 Digital: 25 Pages (2007-07-01)
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Asin: B000VE5T6A
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Editorial Review

Product Description
This digital document is an article from Environmental Health Perspectives, published by Thomson Gale on July 1, 2007. The length of the article is 7374 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Di(2-ethylhexyl) phthalate metabolites may alter thyroid hormone levels in men.(Research)
Author: John D. Meeker
Publication: Environmental Health Perspectives (Magazine/Journal)
Date: July 1, 2007
Publisher: Thomson Gale
Volume: 115Issue: 7Page: 1029(6)

Distributed by Thomson Gale ... Read more


100. Seasonal flux of nonylphenol in Han River, Korea [An article from: Chemosphere]
by D. Li, M. Kim, W.J. Shim, U.H. Yim, J.R. Oh, Kwon
Digital: Pages (2004-07-01)
list price: US$8.95 -- used & new: US$8.95
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Asin: B000RQYPJE
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Editorial Review

Product Description
This digital document is a journal article from Chemosphere, published by Elsevier in 2004. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
In order to understand the behavior of nonylphenol (NP) in Han River, water, suspended particle and sediment samples were analyzed during summer, autumn and winter. Concentrations of nonylphenol in water ranged from 23.2 to 187.6 ng/l, in suspended particle from 6.8 to 190.8 ng/l and in sediment from 25.4 to 932.0 ng/gdrywt. An increasing trend in the concentration is noticed in all matrices along down the river. In case of water and suspended particle, concentrations were higher in warmer season than in colder season. Percentage of nonylphenol in the suspended particle phase decreased from 67% to 28% with decreasing temperature in water. A reasonable correlation (R^2=0.63) was obtained for water and suspended particle. The partition coefficient LogK"p is 4.8. No seasonal variation of the concentration in sediment is noticed in this study. ... Read more


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