Geometry.Net - Nobel: Prusiner Stanley B

Clinical Companion to the Molecular and Genetic Basis of Neurological Disease 2nd Edition. by Robert L. Barchi, Stanley B. Prusiner, Salvatore Dimauro, Robert L. Robert L Barchi, Salvatore Salvatore DiMauro Roger N. Rosenberg, 1998-01-01

Prion Diseases of Humans and Animals

Slow Transmissible Diseases of the Nervous System : Clinical, Epidemiological, Genetic and Pathological Aspects of the Spongiform Encephalopathie by Stanley B., And William J. Hadlow Prusiner, 1979

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? ? ? ? (1942 ) stanley B. prusiner Winner of the nobel Prize in Physiologyor Medicine 1997 For his discovery of Prions - a new biological principle
http://www.networkchinese.com/chineseprof/region/other/uc_camtus/sanfranc/prusin
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1. Autobiographyof stanley B. prusiner. (http//www.nobel.se/medicine/laureates/1997/prusiner
http://microbiology.scu.edu.tw/micro/people/Prusiner.htm
U.S. Neurologist Wins Nobel Prize For Discovery Of Prions
stanley B. prusiner, a maverick mad cow disease in people and animals, Monday wasawarded the ultimate in scientific vindication the nobel Prize in
http://www-tech.mit.edu/V117/N48/nobel.48w.html

Extractions: Stanley B. Prusiner, a maverick American scientist who for two decades endured derision from his peers as he tried to prove that bizarre infectious proteins could cause brain diseases like "mad cow disease" in people and animals, Monday was awarded the ultimate in scientific vindication: the Nobel Prize in Medicine or Physiology. Prusiner, a 55-year-old neurologist at the University of California San Francisco, was cited by the Swedish Nobel committee "for his pioneering discovery of an entirely new genre of disease-causing agents and the elucidation of the underlying principles of their mode of action." The infectious particles that Prusiner discovered, which he named prions (PREE-ons), are made of protein and do not contain any genes or genetic material - a detail that distinguishes them from all other kinds of infectious agents such as viruses, bacteria, fungi and parasites. Until Prusiner came along, no one knew that simple proteins could reproduce themselves as though they were alive. Indeed, the concept was so revolutionary that he was shunned for years as a man who had overreached the limits of scientific sensibility. Many researchers presumed that the diseases Prusiner attributed to prions - including the sheep illness called scrapie and human ailments such as Creutzfeldt-Jakob and kuru - were actually caused by tiny, slow-growing, undiscovered viruses. Although some scientists still question the prion hypothesis, a growing body of work from research laboratories around the world has led to a near-consensus that the feisty Prusiner has been correct all along.
Nobel Laureate Obtains Patents
stanley B. prusiner of the University of California at San prusiners theory holdsthat if some of the experiment will reveal whether the nobel Assembly was
http://www.indianpatents.org.in/ach/nobel.htm

Extractions: Home Achievements Special Studies Nobel Laureate Obtains Patents He has recently obtained another patent entitled "Formation and Use of Prion Protein (PRP) Complexes" on May 12, 1998 for which the application was filed in 1995. The patent relates to a method of screening for compounds which inhibits the binding of PrP to a PrP peptide, comprising the steps of : contacting in-vitro test a compound with a purified naturally occurring first component PrP C in the presence of purified second component PrP peptide, wherein said PrP peptide has random coil or a helical confirmation, and wherein the first and second components form a prion protein complex with a PrP characteristic selected from the group consisting of increased b-sheet content,
Prusiner Stanley B.
stanley B. prusiner, MD, is Director of the Institute for of over 250 research articles,prusiners contributions University (1997); and the nobel Prize in
http://www.mh-hannover.de/aktuelles/projekte/mmm/englishversion/fs_programme/cv/

Extractions: Stanley B. Prusiner, M.D., is Director of the Institute for Neurodegenerative Diseases and Professor of Neurology and Biochemistry at the University of California, San Francisco. He received his undergraduate and medical training at the University of Pennsylvania and his postgraduate clinical training at UCSF. Stanley Prusiner discovered an entirely new class of pathogens that replicate without nucleic acid. Through this work, he created a new field of research that has resulted in significant progress in understanding degenerative diseases of the central nervous system (CNS). His revolutionary studies have made conceptual advances in elucidating mechanisms of age-dependent CNS diseases. For several decades, the prevailing concept was that the transmissible CNS disease scrapie was caused by a slow-acting virus. Prusiner proposed what many scientists considered to be the heretical idea that the scrapie agent, which he called prion, is composed only of protein and is devoid of nucleic acid. His incisive experiments demonstrated how an infectious pathogen lacking nucleic acid can multiply and cause CNS degeneration. After purifying prions from the brain, he discovered that they are composed of a single protein which he called prion protein, or PrP. Prusiner found that a fragment of the protein polymerizes into amyloid; next, he and his colleagues demonstrated that amyloid plaques in the brains of animals and humans dying of prion diseases are composed of PrP. This was the first time that cerebral amyloid was shown to be the cause of a CNS disease.
BSE/kogalskab/prioner
278, 10. October, side 245251. prusiner, stanley B. The prion diseases. februar2000, side 3. Engelbrecht, Nils nobel-pris for deforme proteiner.
http://www.dvjb.kvl.dk/bioinfo/litteraturforslag/bse.htm

Extractions: - en informationstjeneste om bioteknologi og anvendt biologi BSE/Kogalskab/Prioner/CJD Materialerne skal skaffes via folkebiblioteket eller gymnasiebiblioteket Bøger: (på dansk) Bøger: (på engelsk) BSE: The Chaos Continues: The great brain blunder. Af Coghlan, Andy m.fl. New Scientist, 2001, vol. 172, Nr. 2314, side 14-17. Narang, Harash: The Link: from sheep to cow to man: Creutzfeldt-Jakob disease, bovine spongiform encephalopathy, scarpie. Newcastle upon Tyne, H.H. Publisher, 1997, 327 sider. Prion diseases of humans and animals. Redigeret af Stanley Prusiner m.fl. London, Ellis Horwood, 1992, 583 sider.
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Porter, Rodney R. 1972. prusiner, stanley B. 1997. Reichstein, Tadeus, 1950. Richards,Dickinson W. 1956. nobel Prize in Physiology and Medicine Winners 19971901.
http://orel.rsl.ru/archiv/nob_med.htm

Extractions: PHYSIOLOGY AND MEDICINE Alphabetical listing of Nobel prize laureates in Physiology and Medicine Name Year Awarded Adrian, Lord Edgar Douglas Arber, Werner Axelrod, Julius Baltimore, David Banting, Sir Frederick Grant Barany, Robert Beadle, George Wells Behring, Emil Adolf Von Bekesy, Georg Von Benacerraf, Baruj Bergstroem, Sune K. Bishop, J. Michael Black, Sir James W. Bloch, Konrad Blumberg, Baruch S. Bordet, Jules Bovet, Daniel Brown, Michael S. Burnet, Sir Frank Macfarlane Cajal, Santiago Ramon Y Carrel, Alexis Chain, Sir Ernst Boris Claude, Albert Clintock, Barbara Mc Cohen, Stanley Cori, Carl Ferdinand Cori, Gerty Theresa Cormack, Alan M. Cournand, Andre Frederic Crick, Francis Harry Compton Dale, Sir Henry Hallett Dam, Henrik Carl Peter Dausset, Jean De Duve, Christian Delbruck, Max Doherty, Peter C.
Nobel Prizes In Medicine And Physiology
nobel Prizes in Medicine and Physiology. concerning the specificity of the cell mediatedimmune defence (T lymphocytes) 1997 stanley B. prusiner (USA, *194205
http://userpage.chemie.fu-berlin.de/diverse/bib/nobel_medizin_e.html

Extractions: (List, not checked) E. A. v. Behring (Germany) Sir R. Ross (United Kingdom) N. R. Finsen (Denmark) I. P. Pawlow (Russia) R. Koch (Germany) C. Golgi (Italy) (Spain) Ch. L. A. Laveran (France) P. Ehrlich (Germany) I. Metschnikow (France, Russia) Th. Kocher (Switzerland) A. Kassel (Germany) A. Gullstrand (Sweden) A. Carrel (USA, France) Ch. Richet (France) (Austria) J. Bordet (Belgium) A. Krogh (Denmark) A. V. Hill (United Kingdom) O. Meyerhof (Germany) F. G. Banting (Canada) J. J. R. Macleod (Canada) W. Einthoven (Netherlands) J. Fibiger (Denmark) J. Wagner-Jauregg (Austria) Ch. Nicolle (France) Chr. Eijkman (Netherlands) Sir F.G. Hopkins (United Kingdom) K. Landsteiner (USA, Austria) O. H. Warburg (Germany) Ch. S. Sherrington (United Kingdom) E.D. Adrian (United Kingdom) Th. H. Morgan (USA) G. R. Minot (USA) W. P. Murphy (USA) G.H. Whipple (USA) H. Spemann (Germany) Sir H.H. Dale (United Kingdom) Otto Loewi (Austria, 1873-06-03 - 1961-12-25) (Hungary) C. Heymans (Belgium) G. Domagk
E-s-b.com PRION Stanley PRUSINER
_Tiny prion may hold key to deadly brain diseases _Backgrounder on StanleyB. prusiner, MD _Swiss scientists appalled by nobel omission _Collected
http://www.pub-internet.com/ESBprionnobel97.htm
American Wins Nobel Prize For Medicine
conditions won the nobel Prize in medicine. The finding may eventually shed lighton Alzheimer's disease, the prize citation said. stanley B. prusiner of the
http://www.jhu.edu/~newslett/10-09-97/Science/2.html

Extractions: Associated Press STOCKHOLM, Sweden (AP) - An American biologist who discovered the new class of germ that causes "mad cow" disease and other lethal brain-wasting conditions won the Nobel Prize in medicine. The finding may eventually shed light on Alzheimer's disease, the prize citation said. Stanley B. Prusiner of the University of California, San Francisco, was cited for his discovery of prions, "an entirely new genre of disease-causing agents... Prusiner has added prions to the list of well-known infectious agents, including bacteria, viruses, fungi and parasites." The finding was controversial because prions, unlike other germs, contain no genetic material; they are simply proteins. The prize, worth $1 million, is awarded by Sweden's renowned Karolinska Institute. Last year, the British government warned that cattle with so-called mad cow disease were the most likely cause of a variant of Creutzfeldt-Jakob disease, another brain-wasting condition, in people. The CJD variant has killed about 20 people in Europe, nearly all in Britain. The human disease occurred after people ate tainted beef products from cattle that had been fed sheep offal containing prions.
La Revue De L'année 1997
Translate this page Santé (6 de 7). stanley B. prusiner, nobel de médecine 1997. Prix nobel de médecine1997 - stanley B. prusiner Page sur le lauréat stanley B. prusiner.
http://radio-canada.ca/tv/decouverte/14_revue/4f.html
UCSF - Mission Bay - Making History
stanley B. prusiner, UCSF professor of neurology and biochemistry and biophysics,was awarded the nobel Prize in 1997 for his discovery of an entirely new
http://pub.ucsf.edu/missionbay/history/discovery.php

Extractions: HOME BRIEFS Profile Project Timeline Image Database Events, Tours ... Facts NEWS AND FEATURES Building the Campus Moving to Mission Bay Spotlighting Science Creating a New Community ... Making History Print Version UCSF's Road to Discovery UCSF began to develop its stellar research reputation in the 1920s when Karl F. Meyer established the only laboratory in the Western Hemisphere to study plague and encephalitis. UCSF scientists also are credited with discovering vitamin E, developing new dysentery treatments, introducing new anesthetics, mass-producing a plague vaccine for World War II soldiers and establishing the nation's first cancer research center. Now, 80 years later, the road of discovery has become long and distinguished - a fact underlined by the three Nobel prizes awarded UCSF scientists, including Chancellor Mike Bishop, in the last decade for seminal work in cancer and brain disease. The new campus at Mission Bay, and the innovative research programs to take place there and at UCSF's other locations, represent the University's continuing commitment to advance the cause of human health well into the next century. UCSF is the only University of California campus devoted solely to health and biomedical sciences. Today, with it fourfold mission of teaching, research, patient care and community service, UCSF is considered one of the world's premier health science institutions. Its schools of dentistry, medicine, nursing and pharmacy and its graduate division in the biological sciences all rank among the nation's top professional programs.
The Lasker Foundation | Lasker Awards And The Nobel
Year of. Basic Award Winner, Lasker, nobel. George Wells Beadle, 1950, 1958. GeorgeE. Palade, 1966, 1974. stanley B. prusiner, 1994, 1997. Peyton Rous, 1958, 1966.
http://www.laskerfoundation.org/awards/n_vs_l.html

Extractions: The Lasker Medical Science Awards in basic research, clinical research, special achievement and public service, which have been bestowed since l945, provide a chronicle of the progress of biomedical research over the last half-century. The Lasker Foundation is proud that many of the amazing discoveries and achievements of Lasker Award winners are recognized, in addition, by the prestigious Nobel Prize. As of 2002, sixty-six Lasker winners have gone on to win the Nobel.
1990-1999 By David B. Clifford, MD
David B. Clifford, MD. Neurologist and ANA member stanley prusiner's discovery anddescription of prions as was recognized by the award of the nobel Prize in
http://www.aneuroa.org/html/c20html/1990_1999.htm

Extractions: In the 1990's cerebrovascular accidents were the most common destructive neurologic events, resulting in around half of the neurology hospital admissions in major hospitals. In 1995, the first effective intervention for a stroke in progress was demonstrated by Marler and colleagues. Demonstration that tissue plasminogen activator (tPA), administrated to appropriately selected subjects early in the course of a stroke, could significantly reduce the permanent injury marked an important milestone in neurology. Cellular mechanisms of death by necrosis and apoptosis were actively studied, leading to the hope that further protection of the brain will soon be possible. Angioplasty Blood Flow Blood flow scan before and after angioplasty demonstrates enhanced profusion as evidenced by yellow and red coloration in the formerly ischemic (green) hemisphere. The decade of the 90's was also marked by tremendous progress in application of human genetics to neurologic diseases. Perhaps the most striking breakthrough came with the report of the gene locus associated with development of Huntington's disease in 1983 by Guesella and colleagues. Neurologist and ANA member Stanley Prusiner's discovery and description of prions as agents of human and animal diseases, most prominently Creutzfeldt-Jakob Disease and Bovine Spongiform Encephalopathy, was recognized by the award of the Nobel Prize in Medicine in 1997.
Ilia Baskakov
The 1997 nobel Prize to stanley B prusiner for his discovery of Prions a new biological principle of infection . http//www.nobel
http://www.umbi.umd.edu/~mbc/pages/baskakov.htm

Extractions: baskakov@umbi.umd.edu A Postdoctoral position is available immediately to study self-propagating conformational transition of prion proteins. Highly motivated candidates with a background in protein folding and protein chemistry, or cell and molecular biology are encouraged to apply. Experience in two or more areas involving cell culture, immunochemistry, confocal microscopy, protein expression/purification, mass-spectroscopy, basic spectroscopic techniques (CD, fluorescence), electron microscopy is desirable. The Postdoctoral Fellow will be collaborating with other labs and will benefit from working in a stimulating interdisciplinary scientific environment. Please send curriculum vitae and names of three references to Ilia Baskakov, PhD.
Jewish Nobel Prize Winners
1997- stanley B. prusiner; 1998 - Robert F. Furchgott; 2000 - Paul Greengard;
http://www.us-israel.org/jsource/Judaism/nobels.html

Extractions: Jewish Nobel Prize Winners The Nobel Prizes are awarded by the Nobel Foundation of Sweden to men and women who have rendered the greatest service to humankind. Between 1901 and 1995, 663 Nobel Prizes were handed out. Of these, 140 are Jews or people of Jewish descent. 1905 - Adolph Von Baeyer 1906 - Henri Moissan 1910 - Otto Wallach 1915 - Richard Willstaetter 1918 - Fritz Haber 1943 - George Charles de Hevesy 1961 - Melvin Calvin 1962 - Max Ferdinand Perutz 1972 - William Howard Stein Ilya Prigogine 1979 - Herbert Charles Brown 1980 - Paul Berg Walter Gilbert 1981 - Roald Hoffmann 1982 - Aaron Klug 1985 - Albert A. Hauptman
Medizin-Nobelpreis Geht An Prionenforscher - Auszeichnung Für
Translate this page nobelpreis für Medizin dem 55jährigen Amerikaner stanley B. prusiner verliehen. Dezember,dem Todestag des Preisstifters Alfred nobel, in Stockholm
http://www.nzz.ch/dossiers/2001/bse/1997.10.07-vm-article0BQ97.html
Nobel Process Kept Secret
Dario Fo stanley B. prusiner International Campaign can try and guess, but in realitynobody outside the committee has a clue nobel committee observer,
http://archive.abcnews.go.com/sections/world/nobel110_process/
No. 19 -Salvia- PREMIO NOBEL
Translate this page PREMIO nobel. El Premio novel de Medicina 1997 fue otorgado al Dr. stanley B.prusiner, quien se desempeña como profesor de Neurología, Bioquímica y
http://www.insp.mx/salvia/9719/sal97193.html

Extractions: PREMIO NOBEL El Premio novel de Medicina 1997 fue otorgado al Dr. Stanley B. Prusiner, quien se desempeña como profesor de Neurología, Bioquímica y Biofísica en la Universidad de California en San Francisco, California. E sta distinción le fue otorgada por su trabajo pionero en la caracterización de una nueva clase de "agentes infecciosos" que están constituidos de proteínas llamados Priones (proteinaceus infectius particle). Los Prion es don la causa de varias enfermedades neurodegenerativas que afectan al humano (Kuru, enfermedad de Creutzfeldt-Jakob, la enfermedad de Gertsmann-Straussler-Scheinker y el Imsomnio Fatal Familiar) y algunos animales (Scapie y Encefalopatía Espong iforme Bovina-enfermedad de las vacas locas). El Dr. Prusiner ha recibido numerosas distinciones en los que destacan los premios Albert Lasker Basic Medical Research, Potamkin, Wolf, j. Elliot Royer, Ehrlich-drmstaedter, Gairdner Foundation, Charles A. Sana y el Max-Planck, entre o tros. Celso Ramos / CISEI
Bio 385 Fall 1997 - Prions
9f.html. nobel in Medicine stanley B. prusiner and Prions http//192.204.3.5/scitech/prions.shtml.Tutorials. Tutorials - www.micro
http://darwin.bio.geneseo.edu/~simon/bio385/prion.htm

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