1. Medicine 2001 Presentation leland H. hartwell Autobiography Curriculum Vitae nobel LectureInterview nobel Diploma Prize Award Photo Other Resources. Tim http://www.nobel.se/medicine/laureates/2001/

The Nobel Prize in Physiology or Medicine 2001 "for their discoveries of key regulators of the cell cycle" Leland H. Hartwell R. Timothy (Tim) Hunt Sir Paul M. Nurse 1/3 of the prize 1/3 of the prize 1/3 of the prize USA United Kingdom United Kingdom Fred Hutchinson Cancer Research Center Seattle, WA, USA Imperial Cancer Research Fund London, United Kingdom Imperial Cancer Research Fund London, United Kingdom b. 1939 b. 1943 b. 1949 The Nobel Prize in Physiology or Medicine 2001 Press Release Presentation Speech Educational ... Other Resources The 2001 Prize in: Physics Chemistry Physiology or Medicine Literature ... Economic Sciences Find a Laureate: Last modified September 2, 2002 The Official Web Site of The Nobel Foundation

2. Leland H. Hartwell - Autobiography leland H. hartwell – Autobiography. I don't remember much about myearly childhood. I standards. From Les Prix nobel 2001. http://www.nobel.se/medicine/laureates/2001/hartwell-autobio.html

California Institute of Technology . This was my next major break. I took the entrance exams and was admitted into the sophomore class. Howard Temin and Bob Edgar. Another feature of the Cal Tech undergraduate education was the opportunity to take credits as reading which I did most quarters, reading the original literature in phage genetics and gene regulation. I graduated in 1961 and went to MIT for graduate school. I had decided that I wanted to work on gene regulation and I knew of only two prominent labs in the US, Arthur Pardee at Berkeley , and Boris Magasanik, at MIT. I visited Arthur Pardee at Berkeley and he was not encouraging so I went to MIT. Being a graduate student at MIT was great fun and very intense. Boris Magasanik would come through the lab each afternoon and stop at each desk to discuss the previous day's results. I wanted a new result each day so that set quite a pace! I was there only about two and a half years when Boris came to me and said that I had essentially finished my thesis but since no one could leave that soon I would have to stay another year. By this time had published their famous work on the lac operon and I figured that gene regulation was pretty well understood. I thought it appropriate to do my postdoctoral work on something much less well understood and I decided to work on the control of cell growth. Going to the literature again, I was most impressed with the work coming out of

3. Leland H. Hartwell Winner Of The 2001 Nobel Prize In Physiology Or Medicine leland H. hartwell, the 2001 nobel Prize Laureate in Physiology or Medicine,at the nobel Prize Internet Archive. leland H. hartwell. http://almaz.com/nobel/medicine/2001a.html

L ELAND H. H ARTWELL Nobel Laureate in Physiology or Medicine for their discoveries of "key regulators of the cell cycle." Background Born: October 30, 1939 Place of birth: Los Angeles, CA, USA Residence: U.S.A. Affiliation: Fred Hutchinson Cancer Research Center Address: Fred Hutchinson Cancer Research Center University of Washington, Seattle 1100 Fairview Ave N; D1-060 Seattle, WA 98109 Telephone: (206) 667-5670 FAX: (206) 667-5268 E-mail: lhartwel@fhcrc.org Education: California Institute of Technology , B.S. 1961 Massachusetts Institute of Technology , Ph.D. 1964 Book Store Genomic Instability and Immortality in Cancer (Pezcoller Foundation Symposia, 8) The Harvey Lectures Series 90 Genetics: From Genes to Genomes Solutions Manual/Study Guide t/a Genetics: From Genes to Genomes ... Books on Regulators of the Cell Cycle Featured Internet Links Prize co-recipient: R. Timothy Hunt Prize co-recipient: Paul M. Nurse PubMedline search results for this laureate Web Page at Fred Hutchinson Cancer Research Center ... Official award announcement and background Search WWW Search The Nobel Prize Internet Archive Links added by Nobel Internet Archive visitors CNN story Fred Hutchinson Back to The Nobel Prize Internet Archive Literature ... Medicine We always welcome your feedback and comments

4. Index Of Nobel Laureates In Medicine ALPHABETICAL LISTING OF nobel PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE.Name, Year Awarded. Hartline, Haldan Keffer, 1967. hartwell, leland H. 2001. http://almaz.com/nobel/medicine/alpha.html

ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE Name Year Awarded Adrian, Lord Edgar Douglas Arber, Werner Axelrod, Julius Baltimore, David ... Medicine We always welcome your feedback and comments

5. 2001 Nobel Laureate Leland H. Hartwell To Give University Of Pittsburgh School O Back. 2001 nobel LAUREATE leland H. hartwell TO GIVE UNIVERSITY OFPITTSBURGH SCHOOL OF MEDICINE'S 82nd MELLON LECTURE PITTSBURGH http://www.upmccancercenters.com/news/upci_news/2002/050602_medschool_mellon.htm

Search News and Events Back 2001 NOBEL LAUREATE LELAND H. HARTWELL TO GIVE UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE'S 82nd MELLON LECTURE PITTSBURGH, May 06 Leland H. Hartwell, PhD, president and director of the Fred Hutchinson Research Center at the University of Washington, will present the University of Pittsburgh School of Medicine's 82nd Mellon Lecture at 4 p.m. Monday, June 10, in Lecture Room 6, Scaife Hall, 3550 Terrace St., Oakland. Dr. Hartwell's lecture was originally scheduled as part of last September's Science 2001 - A Research Odyssey, a showcase of research at the University of Pittsburgh. After completing his PhD at M.I.T., Dr. Hartwell began his professional research at the Salk Institute, but it wasn't until he moved to the University of California at Irvine that he began his work with yeast. In 1996, he joined the Fred Hutchinson Cancer Research Center and the faculty of the University of Washington as a professor of genetics. Dr. Hartwell has received numerous awards and honors over the course of his career including the Brandeis University Rosensteil Award, the Sloan-Kettering Cancer Center Katherine Berkan Judd Award, the Genetics Society of America Medal, the MGH Warren Triennial Prize, the Columbia University Horwitz Award, the Passano Award and the Albert Lasker Award for medical research.

6. 2001 Nobel Laureate Leland H. Hartwell To Give University Of Pittsburgh School O Back to UPCISpecific News. 2001 nobel LAUREATE leland H. hartwell TO GIVEUNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE'S 82nd MELLON LECTURE http://www.upci.upmc.edu/internet/news/upci_news/2002/050602_medschool_mellon.ht

Back to UPCI-Specific News 2001 NOBEL LAUREATE LELAND H. HARTWELL TO GIVE UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE'S 82nd MELLON LECTURE PITTSBURGH, May 06 Leland H. Hartwell, PhD, president and director of the Fred Hutchinson Research Center at the University of Washington, will present the University of Pittsburgh School of Medicine's 82nd Mellon Lecture at 4 p.m. Monday, June 10, in Lecture Room 6, Scaife Hall, 3550 Terrace St., Oakland. Dr. Hartwell's lecture was originally scheduled as part of last September's Science 2001 - A Research Odyssey, a showcase of research at the University of Pittsburgh. Dr. Hartwell's lecture, "From Yeast Cell Division to Human Cancer: The Unity of Biology," will focus on his work using baker's yeast to study fundamental biological processes such as cell division and growth. He was awarded the Nobel Prize for his seminal discovery of cell cycle checkpoints - a major advance in understanding the mechanisms controlling cell growth. These checkpoints notice when mistakes have been made during cellular reproduction and halt cell division so that repairs can take place. Dr. Hartwell's ideas and experimental work have stimulated new research initiatives by many laboratories around the world and have been instrumental in the development of therapeutic strategies for diseases caused by uncontrolled cell growth.

7. NIGMS -- News & Events: NIH Grantee Leland Hartwell Wins Nobel Prize For Breakth Dr. leland H. hartwell, a longtime grantee of the National Institutes of Health,was awarded the 2001 nobel Prize in Physiology or Medicine today for his http://www.nigms.nih.gov/news/releases/nobel_hartwell.html

skip navigation NIGMS Home What's New Site Map ... Search NIGMS for: Text size: A A A Research Funding ... E-mail this link NIH Grantee Leland Hartwell Wins Nobel Prize for Breakthroughs in Understanding the Cell Cycle by Ann Dieffenbach October 8, 2001 Dr. Ruth L. Kirschstein, acting director of NIH, said, "I am thrilled that Dr. Hartwell has received this high honor. He is a fine human being and an exceptional scientist who is dedicated to training new generations of researchers. His work has led to an explosion of knowledge on how cells precisely manage a process that is crucial to life. As a result, we have a deeper understanding of normal cellular function as well as the molecular basis of diseases, like cancer and some birth defects, in which cell division goes awry. We also have new directions to pursue in developing drugs to target these diseases." The Nobel Assembly of the Karolinska Institute in Stockholm, Sweden, announced the prizes this morning. Dr. Hartwell, president and director of the Fred Hutchinson Cancer Research Center in Seattle and professor of genetics at the University of Washington, also in Seattle, received the award jointly with Dr. Paul M. Nurse and Dr. R. Timothy Hunt, both of the Imperial Cancer Research Fund in London. Dr. Hartwell has used a simple, one-celled organism

8. Leland Hartwell Awarded Nobel nobel in medicine. By Tim Klass, The Associated Press 10/8/01. SEATTLE When hefirst started doing research on cell division in yeast, Dr. leland H. hartwell ( http://www.its.caltech.edu/~alumni/hartwell.htm

close window Hutchinson center's Leland Hartwell awarded Nobel in medicine By Tim Klass, The Associated Press 10/8/01 SEATTLE - When he first started doing research on cell division in yeast, Dr. Leland H. Hartwell (Caltech Alum: BS61BI) felt "alone in the woods." Today, the president and director of the Fred Hutchinson Cancer Research Center and professor of genetics at University of Washington in Seattle took his place with the giants as co-winner of the Nobel Prize for medicine. He shares the $943,000 prize with R. Timothy Hunt and Paul Nurse of the Imperial Cancer Research Fund in England for basic discoveries in cell development. Hartwell said he was sleeping early today when a Hutchinson staffer called to give him the news. "It struck like a thunderbolt," he said. "The most significant aspect is the finding by many people of the relationship between very simple cells, like yeast cells, and human cells, the fact that very simple cells and human cells are closely related," Hartwell said. He said he was indebted to some 30 former graduate and postdoctoral students, "all the students in my lab who contributed to my work over the years."

9. Leland H. Hartwell - CIRS leland H. hartwell is widely Awards 2001 nobel Prize in physiology or medicine,2000 Massry Prize, 2000 Leopold Griffuel Prize, 1999 American Cancer http://www.cirs.net/researchers/medicine/HARTWELL.htm

HARTWELL, LELAND H. lhartwel@fhcrc.org President and Director of the the Fred Hutchcinson Cancer Research Center , Seattle, WA, USA, University of Washington American Cancer Society Research Professor of Genetics. Research interests : His work over the last 30 years, using yeast as a model organism, forms the foundation upon which today's detailed knowledge of the molecular mechanisms controlling the cell division cycle in nucleated cells rests. Dr. Hartwell's discovery of genes regulating the orderly progression of the cell cycle has had a major influence on our understanding of cancer and the therapeutic strategies used to treat diseases caused by uncontrolled cell growth. Leland H. Hartwell is widely recognized as a pioneer in the field of yeast genetics and cancer research. Since then, his discoveries have profoundly affected the understanding of human cell growth and cancer. He and his colleagues are studying yeast cells to determine if lack of a cell's control over certain points in its division sequence may contribute to cancer. He also is examining the role of hormones in controlling cell growth. Awards : 1983-1984 Guggenheim Awardee and American Cancer, 1973 Eli Lilly Award in Microbiology and Immunology.

10. Medyczny Nobel 2001 leland H. hartwell, R. Timothy Hunt, Paul M. Nurse. Zgromadzenie NagrodyNobla w Instytucie Karolinskim postanowilo, ze Nagrode http://www.nil.org.pl/xml/nil/gazeta/numery/n2001/n200111/n20011105

window.onresize=resizeHandler; Numer 2001-11 S³owo Redaktora Naczelnego Mariusz £apiñski nowym ministr... Oczekiwania, potrzeby i nadzie... ... Medycy w parlamencie Medyczny Nobel 2001 By³y tylko obietnice... Zintegrowany system ratownictw... Pociecha dla cierpi±cych na SM Szpital z dusz± ... Dy¿urny pacjent kraju Medyczny Nobel 2001 showpic('center','','','','img/nil/gazeta/n200111/np20011105a_small.jpg','img/nil/gazeta/n200111/np20011105a.jpg'); showpic('center','','','','img/nil/gazeta/n200111/np20011105b_small.jpg','img/nil/gazeta/n200111/np20011105b.jpg'); showpic('center','','','','img/nil/gazeta/n200111/np20011105c_small.jpg','img/nil/gazeta/n200111/np20011105c.jpg'); Leland H. Hartwell R. Timothy Hunt Paul M. Nurse Zgromadzenie Nagrody Nobla w Instytucie Karoliñskim postanowi³o, ¿e Nagrodê Nobla za rok 2001 w dziedzinie medycyny i fizjologii otrzymaj± wspólnie Leland H. Hartwell, R. Timothy Hunt i Paul M. Nurse za odkrycie "najwa¿niejszych regulatorów cyklu cz±steczkowego" Tegoroczni laureaci Nagrody Nobla w dziedzinie fizjologii i medycyny dokonali wa¿nych odkryæ dotycz±cych mechanizmów reguluj±cych cykl rozwoju komórki. Wyró¿nieni uczeni odkryli cz±steczki reguluj±ce cykl rozwoju komórek wszystkich organizmów eukariotycznych - dro¿d¿y, ro¶lin, zwierz±t, a tak¿e cz³owieka. Ich fundamentalne odkrycia maj± podstawowe znaczenie dla wszystkich aspektów wiedzy o rozwoju komórki. Zaburzenia regulacji cyklu komórkowego mog± prowadziæ do wyst±pienia w chromosomach defektów spotykanych w komórkach rakowych. W przysz³o¶ci dokonania tegorocznych laureatów mog± otworzyæ nowe mo¿liwo¶ci leczenia nowotworów - czytamy w oficjalnym komunikacie Zgromadzenia Nagrody Nobla.

11. Pitt Campaign Chronicle: 2001 Nobel Laureate Is Mellon Lecturer 2001 nobel Laureate Is Mellon Lecturer leland H. hartwell. By JocelynUhl. leland H. hartwell, president and director of the Fred http://www.discover.pitt.edu/media/pcc020520/mellonlecturer.html

HOME NEXT ARTICLE 2001 Nobel Laureate Is Mellon Lecturer Leland H. Hartwell By Jocelyn Uhl Hartwell has received numerous awards and honors over the course of his career, including the Brandeis University Rosensteil Award, the Sloan-Kettering Cancer Center Katherine Berkan Judd Award, the Genetics Society of America Medal, the MGH Warren Triennial Prize, the Columbia University Horwitz Award, the Passano Award, and the Albert Lasker Award for medical research. Funds originally provided by the late R.B. Mellon and the Sarah Mellon Scaife and Richard King Mellon foundations have enabled the University of Pittsburgh School of Medicine to recognize an eminent investigator in the medical sciences each year for the past eight decades. HOME NEXT ARTICLE University of Pittsburgh University of Pittsburgh Home Search Finding People Top of Page

12. Pitt Campaign Chronicle: 2001 Nobel Laureate leland H. hartwell, center, president and director of the Fred Hutchinson CancerResearch Center in Seattle, talks hartwell was awarded the nobel Prize for http://www.discover.pitt.edu/media/pcc020701/nobel2001.html

HOME NEXT ARTICLE 2001 Nobel Laureate HOME NEXT ARTICLE University of Pittsburgh University of Pittsburgh Home Search Finding People Top of Page

13. C&EN: NEWS OF THE WEEK - REGULATORS OF THE CELL CYCLE year's nobel Prize in Physiology or Medicine for discovering the molecular mechanismsthat regulate the cell cycle in higher organisms. leland H. hartwell, 61 http://pubs.acs.org/cen/topstory/7942/7942notw2.html

Home This Week's Contents Nobel Prize ASYMMETRIC CATALYSIS WINS REGULATORS OF THE CELL CYCLE COLD ATOMS ARE HOT, HOT, HOT Related People Leland H. Hartwell R. Timothy Hunt Paul M. Nurse E-mail this article to a friend ... Science/Technology Concentrates Business Science/Technology Education ACS News ... Chemcyclopedia Back Issues How to Subscribe Subscription Changes E-mail webmaster NEWS OF THE WEEK NOBEL PRIZE October Volume 79, Number 42 CENEAR 79 42 p. 6 ISSN 0009-2347 [Previous Story] [Next Story] REGULATORS OF THE CELL CYCLE Discovery of cyclins, cyclin-dependent kinases earns medicine Nobel Prize REBECCA RAWLS Two geneticists and a biochemist will share this year's Nobel Prize in Physiology or Medicine for "discovering the molecular mechanisms that regulate the cell cycle" in higher organisms. Leland H. Hartwell , 61, president and director of the Fred Hutchinson Cancer Research Center, Seattle, and professor of genetics at the University of Washington, will share the approximately $950,000 prize with biochemist R. Timothy Hunt

14. Zellzyklus Translate this page leland H. hartwell hat diesen Start-Punkt entdeckt und den Die Erkenntnisse von hartwell,Hunt und Nurse bilden Die nobel-Stiftung im Internet www.nobel.se. http://www.vcell.de/welt_der_zelle/zellzyklus.html

Welt der Zelle Unendliche Vielfalt Zellzyklus glossar sitemap kontakt Anwendung ... TopThema Zellzyklus Alle Schalter auf Start Zum hundertsten Geburtstag der Nobelpreise rückte ein besonders wichtiges Forschungsfeld in den Blickpunkt: Die Krebsforscher Leland H. Hartwell (USA) sowie R. Timothy Hunt und Sir Paul M. Nurse (beide Großbritannien) werden für ihre Erkenntnisse über den Zellzyklus und seine Kontrolle mit dem Nobelpreis für Medizin ausgezeichnet. Auch beim erwachsenen Menschen müssen Zellen sich teilen können, um abgestorbene Zellen ersetzen zu können. Leland H. Hartwell Dieser Prozess muss jedoch streng kontrolliert sein. So werden Hautzellen ständig abgestoßen und ersetzt, Leberzellen teilen sich praktisch nur noch, um Wunden zu schließen, und Nervenzellen teilen sich im erwachsenen Menschen überhaupt nicht mehr. Wenn sich eine Zelle dieser Wachstumskontrolle entzogen hat, ist der Weg zur Entstehung von Krebs bereitet. Der wichtigste Kontrollpunkt im Zellzyklus ist der Eintritt in die Synthese-Phase (S-Phase), in der das Erbgut der Zelle verdoppelt wird. Ist dieser Punkt einmal überwunden, teilt sich die Zelle – komme, was wolle. Leland H. Hartwell hat diesen Start-Punkt entdeckt und den Begriff „Checkpoint“ für die weiteren Kontrollpunkte geprägt. R. Timothy Hunt

15. Nobel 2001 zajmujacy sie cyklem komórkowym leland H. hartwell, R Trzydziesci lat temuleland hartwell opisal pierwsza kinaze LH hartwell, R. Tim Hunt, P. Nurse. http://www.biologia.pl/nowosci/nobel_2001.phtml

Biochemia Biotechnologia Fizjologia Genetyka ... O nas Tu jeste¶: Biologia.pl Sygna³y - Inne Nobel 2001 Ósmego pa¼dziernika 2001 roku ¶wiat dowiedzia³ siê, ¿e nagrodê Nobla w dziedzinie fizjologii i medycyny otrzymali trzej naukowcy zajmuj±cy siê cyklem komórkowym : Leland H. Hartwell, R. Timothy Hunt i Paul Nurse. ¯ycie ka¿dej dziel±cej siê komórki sk³ada siê z powtarzaj±cych siê okresów. Ka¿dy taki okres - pojedynczy cykl komórkowy - mo¿na podzieliæ na cztery g³ówne czê¶ci: fazê , w której komórka przygotowuje siê do kopiowania w³asnego materia³u genetycznego i decyduje, czy siê podzieliæ; fazê S , czyli replikacjê DNA; fazê G2, w której komórka przygotowuje siê do podzia³u, i sam podzia³, czyli mitozê (fazê M). Obie komórki powstaj±ce podczas mitozy wchodz± do fazy G1. Przechodzenie komórki przez taki cykl jest kontrolowane przez trzy podstawowe grupy bia³ek: kinazy cyklinozale¿ne (enzymy, które zmuszaj± komórkê do wej¶cia do nastêpnej fazy cyklu komórkowego dziêki fosforylacji wybranych bia³ek), cykliny (bia³ka, które uruchamiaj± kinazy cyklinozale¿ne, a pod koniec cyklu s± niszczone przez komórkê) i inhibitory cdk, które hamuj± kinazy cyklinozale¿ne. Tegoroczni Nobli¶ci odkryli dwie z tych trzech rodzin bia³kowych (kinazy cyklinozale¿ne i cykliny) oraz rozpoczêli badania nad punktami kontrolnymi cyklu komórkowego. Trzydzie¶ci lat temu Leland Hartwell opisa³ pierwsz± kinazê cyklinozale¿n± u dro¿d¿y S. cerevisiae oraz przeprowadzi³ wstêpne badania, które wykaza³y, ¿e uszkodzenie DNA przez promieniowanie jonizuj±ce prowadzi do zatrzymania cyklu komórkowego, ¿eby komórki ze zniszczonym materia³em genetycznym nie mog³y siê podzieliæ. Paul Nurse odkry³, ¿e komórki dro¿d¿y S. pombe i cz³owieka zawieraj± podobne kinazy cyklinozale¿ne, a Tim Hunt jako pierwszy opisa³ cykliny.

16. Hadiah Nobel Kedokteran 2001 -- Jumat, 2 November 2001 Atas jasa leland H hartwell, R Timothy Hunt, dan Paul Nurse, yang telah memperolehhadiah nobel kedokteran 2001 inilah, kita akan semakin memahami sebagian http://www.kompas.com/kompas-cetak/0111/02/iptek/hadi38.htm

- Kompas Hari Ini - Berita Hari Ini Berita Sebelumnya Mencari Berita Tentang Kompas Kontak redaksi Kompas CyberMedia - R U B R I K - Berita Utama Nasional Nusantara Dikbud Ekonomi Iptek Kurs Mata Uang Internasional Metropolitan Naper Olahraga Opini Jawa Timur Jawa Tengah English Nederlands >Jumat, 2 November 2001 Hadiah Nobel Kedokteran 2001 Merenungkan kembali tubuh kita mengingatkan pada betapa banyak hal yang belum maupun sudah kita sudah ketahui. Pada mulanya tubuh kita yang "gede" ini berasal dari sel tunggal, yaitu sel telur yang dibuahi sel sperma. Seiring dengan waktu, sel membelah terus-menerus, sampai pada akhirnya lahir bayi yang sempurna. Tentu saja peristiwa pembelahan sel tidak otomatis berjalan begitu saja, ada suatu mekanisme yang mengontrolnya. Atas jasa Leland H Hartwell, R Timothy Hunt, dan Paul Nurse, yang telah memperoleh hadiah Nobel kedokteran 2001 inilah, kita akan semakin memahami sebagian dari misteri penciptaan Tuhan itu. Mereka bertiga telah berjasa atas temuan berupa molekul pengendali siklus sel yang terjadi pada semua organisme eukariot (ragi, tanaman, hewan, dan manusia). Penemuan-penemuan itu terjadi kala mereka masih berusia muda. Mari kita simak mereka itu. Prof Leland H Hartwell lahir tahun 1939. Gelar PhD diraih pada usia 25 tahun dari Massachuset Institute of Technology. Empat tahun kemudian ia sudah diangkat sebagai profesor di Universitas Washington. Beberapa penghargaan pernah ia terima seperti Genetics Society of America Medal (1994) dan The Albert Laker Basic Medical Research Award (1998).

17. Merck Sharp & Dohme - Argentina Translate this page Felicitaciones al Dr. leland H. hartwell, ganador del premio nobel de Medicina2001 El Dr. hartwell, norteamericano, quien compartió la distinción de la http://www.msd.com.ar/empresa/sala/institucional/tenoticia11.htm

Institucional Asma Enfermedades Reumáticas y Dolor Agudo Hipercolesterolemia ... Osteoporosis Felicitaciones al Dr. Leland H. Hartwell, ganador del premio Nobel de Medicina 2001 Whitehouse Sation, N. J., 9/10/2001. El Dr. Leland H. Hartwell, reciente ganador del premio Nobel de Medicina y director del Centro de Investigación del Cáncer Fred Hutchinson, de Seattle, fue uno de los investigadores que desarrollaron las tecnologías claves que dieron origen a la fundación de Rosetta Inpharmatics, Inc. El Dr. Hartwell convocó a un investigador de Merck, Stephen Friend, quien estaba trabajando en Harvard, para que se integrara a su equipo de trabajo en el Centro de Investigación en Cáncer Fred Hutchinson, particularmente e el Proyecto Seattle. Fue precisamente mientras trabajaban en este proyecto que desarrollaron un método para examinar un amplio número de genes, una técnica que permite a los investigadores determinar si un medicamento está actuando donde se lo necesita. Juntos fundaron Rosetta Inpharmatics, laboratorio en el que también hizo contribuciones relevantes el Dr. Lee Hood, quien desarrolló una técnica de inyección de tinta para imprimir huellas de genes en pequeños dispositivos diseñados especialmente. Índice

18. Mellon Lecture - News Release FOR IMMEDIATE RELEASE. 2001 nobel LAUREATE leland H. hartwell TO GIVEUNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE'S 82nd MELLON LECTURE. http://www.health.pitt.edu/content/hartwell-pr.htm

UPMC Health System News Bureau FOR IMMEDIATE RELEASE 2001 NOBEL LAUREATE LELAND H. HARTWELL TO GIVE UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE'S 82nd MELLON LECTURE PITTSBURGH, May 6 - Leland H. Hartwell, Ph.D., president and director of the Fred Hutchinson Research Center at the University of Washington, will present the University of Pittsburgh School of Medicine's 82nd Mellon Lecture at 4:00 p.m. Monday, June 10, in Lecture Room 6, Scaife Hall, 3550 Terrace St., Oakland. Dr. Hartwell's lecture was originally scheduled as part of last September's Science 2001 - A Research Odyssey, a showcase of research at the University of Pittsburgh. Dr. Hartwell's lecture, "From Yeast Cell Division to Human Cancer: The Unity of Biology," will focus on his work using baker's yeast to study fundamental biological processes such as cell division and growth. He was awarded the Nobel Prize for his seminal discovery of cell cycle checkpoints - a major advance in understanding the mechanisms controlling cell growth. These checkpoints notice when mistakes have been made during cellular reproduction and halt cell division so that repairs can take place. Dr. Hartwell's ideas and experimental work have stimulated new research initiatives by many laboratories around the world and have been instrumental in the development of therapeutic strategies for diseases caused by uncontrolled cell growth.

19. News - 15 Nov 2002 2001 nobel Laureate Visits IMCB Professor leland H. hartwell. 1 Nov2002. Abstract IMCB welcomed Professor leland H. hartwell as a http://www.imcb.nus.edu.sg/news_events/newsfile/Hartwell.html

20. Medicine-Worldwide: Hartwell - Hunt - Nurse Translate this page leland H. hartwell. Die drei Wissenschaftler, leland hartwell, Timothy Hunt und PaulNurse, sind Dezember, dem Todestag des Preisstifters Alfred nobel (1833-1896 http://www.medicine-worldwide.de/persoenlichkeiten/hartwell_hunt_nurse.html

Sie befinden sich hier: startseite persoenlichkeiten Medizingeschichte H istorisches zur Harnschau M eilensteine der Medizingeschichte ... Über uns Biographie Leland H. Hartwell R. Timothy ("Tim") Hunt Sir Paul M. Nurse Leland H. Hartwell Neurologe Leland H. Hartwell * 30. Oktober 1939 in den USA R. Timothy ("Tim") Hunt Biochemiker * 19. Februar 1943 in England Sir Paul M. Nurse Biologe * 25. Januar 1949 in England Die drei Wissenschaftler, Leland Hartwell, Timothy Hunt und Paul Nurse, sind die Inhaber des 100. Nobelpreises für Medizin im Jahre 2001, der traditionsgemäß am 10. Dezember, dem Todestag des Preisstifters Alfred Nobel (1833-1896) in Stockholm verliehen wird. Den 1. Nobelpreis für Medizin hatte Emil von Behring (1854-1917) 1901 für seine Leistungen auf dem Gebiet der Serumtherapie der Diphtherie erhalten. Die drei diesjährigen Wissenschaftler erhielten den Preis für die Erforschung der molekularen und biochemischen Ursprünge bei der Zellteilung. "Mit ihren Erkenntnissen haben die Forscher wichtige Grundlagen für die Bekämpfung von Tumoren gelegt", erklärte das Stockholmer Karolinska Institut zur Begründung. Die Nobelpreisträger hatten in den 1970er und 80er Jahren die entscheidenden Komponenten des Zellzyklus der Zellteilung in genetisch verschiedene Abschnitte aufgedeckt. R. Timothy Hunt

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