41. The Johns Hopkins Gazette October 16, 2000 paul greengard at the Biophysics Department's 50th anniversary celebration in greengarddidn't know it then, but he'd of science's highest awards a nobel Prize http://www.jhu.edu/~gazette/2000/oct1600/16nobel.html

October 16, 2000 VOL. 30, NO. 7 Nobel Prize Awarded to One of Hopkins' First Ph.D.'s in Biophysics By Michael Purdy Homewood Five decades ago, Paul Greengard was facing a tough decision. Greengard had just earned an undergraduate degree in physics and was planning to go on to graduate school, but he was worried that a graduate degree in physics would inevitably lead to work in the atomic weapons industry. Greengard, a veteran who had served in the Navy in World War II, found the prospect unsettling. He had heard word, though, of a unique new graduate program at the University of Pennsylvania. The program was in a new discipline of sciencebiophysicsthat was cross-pollinating physics and biology by applying the principles of atomic physics and other areas of physical research to problems in biology. Paul Greengard at the Biophysics Department's 50th anniversary celebration in June 1999. Greengard didn't know it then, but he'd just set his feet on a path that would lead to The Johns Hopkins University, and, 50 years later, to one of science's highest awards: a Nobel Prize. Early last week, Greengard, now the director of the Laboratory of Cellular and Molecular Neuroscience at Rockefeller University, learned that the Nobel Prize committee in Stockholm had named him one of three co-recipients of the prize in physiology or medicine. All were cited for the insights they have developed into the basic workings of the brain and the nervous system.

42. Krieger School Of Arts & Sciences ve been guilty myself, in many instances, of thinking, when some new exciting ideacomes along, This can't be right, says nobel laurete paul greengard PhD '53 http://www.jhu.edu/~as1/website/aboutksas/publications/update/spring02/eyealumni

Publications , Spring 2002 UPDATE Archive Eye on Alumni A Nobel Gesture This Eye on Alumni introduces readers to Paul Greengard, winner of the 2000 Nobel Prize in Physiology or Medicine. Greengard, who in 1953 earned his PhD in the School of Arts and Sciences' young Department of Biophysics (in 1957 to be named the Thomas C. Jenkins department; see May '99 UPDATE In October, UPDATE interviewed Greengard in his lab at The Rockefeller University in New York City. His Bernese mountain dog, Meesh, at his side (Meesh is a regular at Rockefeller), Greengard talked about his work in the lab, about winning the Nobel Prize, and about using the reward to further an ideal. "I've been guilty myself, in many instances, of thinking, when some new exciting idea comes along, "This can't be right," says Nobel laurete Paul Greengard PhD '53. (Photo courtesy of The Rockefeller University) Who: Paul Greengard PhD '53 What: Vincent Astor Professor and head of the Laboratory of Molecular and Cellular Neuroscience at The Rockefeller University; Director, Zachary and Elizabeth M. Fisher Center for Research on Alzheimer's Disease at Rockefeller; winner of the 2000 Nobel Prize in Physiology or Medicine.

43. 3 Share Nobel Prize In Medicine For Studies Of The Brain Don Hogan Charles/ The New York Times. Dr. paul greengard of New York, oneof the three recipients of the nobel Prize in Physiology or Medicine. http://plaza1.snu.ac.kr/~bklife/php/documents/CLS-kaang-13-nytimes.html

October 10, 2000 3 Share Nobel Prize in Medicine for Studies of the Brain By NICHOLAS WADE Don Hogan Charles/ The New York Times Dr. Paul Greengard of New York, one of the three recipients of the Nobel Prize in Physiology or Medicine. Related Articles The New York Times on the Web: Science/Health Forum Join a Discussion on Science in the News Web Resource Nobel Assembly Statement Don Hogan Charles/ The New York Times Dr. Eric R. Kandel of New York is also one of the three recipients of the Nobel Prize in Physiology or Medicine. hree scientists who have made important contributions to understanding the long-term changes in the brain that underlie memory and mood were awarded the Nobel Prize in Physiology or Medicine yesterday. Dr. Arvid Carlsson of the University of Gothenberg in Sweden and two New Yorkers, Dr. Eric R. Kandel of Columbia University and Dr. Paul Greengard of Rockefeller University, will share prize money of nine million Swedish crowns, or $914,700. Dr. Carlsson, 77, discovered that dopamine was an important chemical signal in the region of the brain that controls movement, a discovery that laid the basis for finding that the agent is depleted in patients with Parkinson's and that the disease could be treated with the drug L- dopa. Dr. Kandel, 70, has worked to understand the changes that take place in brain cells when memories are formed. Dr. Greengard, 74, has focused on unraveling the intricate cascade of events that occurs inside a neuron after a signal is received.

44. Paul Greengard Translate this page paul greengard é o 21º laureado com o prêmio nobel da UniversidadeRockefeller, um dos primeiros centros mundiais de pesquisa. http://www.terra.com.br/mundo/2000/10/11/059.htm

45. Nobel De Medicina Los Cerebros Que Estudian El Cerebro Translate this page El Premio nobel de Fisiología y Medicina 2000 fue otorgado a tres investigadores-Arvid Carlsson, paul greengard y Eric Kandel- que se han asomado a los http://www.buenasalud.com/lib/ShowDoc.cfm?LibDocID=3412&ReturnCatID=15

46. INDEX nobel Prize. nobel prize. nobel prize. nobel, Alfred. OPAC. Oracle 91. Particlephysics. paul Ehrenfest. paul greengard. PHOBOS detectors. Photons. Pieter Zeeman. http://202.41.94.163/nov00/

INDEX A.F. Ioffe AACR-II Accelerator network Alan G. MacDiarmid ... / Contents

47. Kurier Elektroniczny Medycyny Praktycznej - Nobel 2000 W nobel 2000 w dziedzinie fizjologii i medycyny. Nalezy podkreslic, ze wprawdzieArvid Carlsson, paul greengard i Eric Kandel dokonali odkryc na polu badan http://www.mp.pl/kurier/show.php?aid=1104

48. EMF Announcements Scientific Advisory Board member Eric R. Kandel and Senior Scholar awardeepaul greengard share nobel Prize, Eric R Kandel, paul greengard. http://www.ellison-med-fn.org/announcement_detail.jsp?announcement_id=4

49. Science News: Nobel 2000 00) Three neuroscientists will share this year's nobel Prize for Carlsson, Departmentof Pharmacology, University of Gothenburg; paul greengard, Laboratory of http://www.accessexcellence.org/WN/SUA14/nobel2k.html

Nobels to Brain Researchers By Sean Henahan , Access Excellence Washington, DC Three neuroscientists will share this year's Nobel Prize for medicine for their pioneering studies of neurotransmitters, research that led the way to a better understanding of neurological diseases and the developments of treatments for Parkinson's disease and depression. The new laureates are Arvid Carlsson, Department of Pharmacology, University of Gothenburg; Paul Greengard, Laboratory of Molecular and Cellular Science, Rockefeller University, New York; and Eric Kandel, Center for Neurobiology and Behavior, Columbia University, New York. Each of the awardees was recognized for his specific contributions to the understanding of how nerve cells communicate. In particular, the scientists all helped elucidate one type of signal transduction known as slow synaptic transmission. The neurotransmitter dopamine plays a key role in this process. Some of the drugs that were developed thanks to the research in this area include L-Dopa, a standard treatment for Parkinson's disease, and the antidepressant fluoxetine (Prozac). Dr. Carlsson is credited for the critical discovery that dopamine is a transmitter in the brain that plays an essential role in muscle movement. He has also mad important discoveries regarding the pathogenesis of schizophrenia. Dr. Greengard's research elaborated the mechanism of action of dopamine and other transmitters. He determined that a neurotransmitter interacts with a cell surface receptor, triggering a cascade of reactions that activate regulatory proteins. Phosphorylation and dephosphorylation of these proteins changes their shape and function, facilitating the transmission of signals through the nervous system. Dr. Kandel, for his part, made important discoveries regarding the modification of the efficiency of synapses, providing important new information on short and long-term memory.

50. Nobel 2000 nobel 2000. caly swiat dowiedzial sie, ze tegoroczna nagrode Nobla w dziedziniefizjologii i medycyny otrzymali Arvid Carlsson, paul greengard i Eric http://www.biologia.pl/nowosci/nobel_2000.phtml

Biochemia Biotechnologia Fizjologia Genetyka ... O nas Tu jeste¶: Biologia.pl Sygna³y - Inne Nobel 2000 Na pocz±tku pa¼dziernika ca³y ¶wiat dowiedzia³ siê, ¿e tegoroczn± nagrodê Nobla w dziedzinie fizjologii i medycyny otrzymali Arvid Carlsson, Paul Greengard i Eric Kandel - naukowcy, którzy odkryli mechanizm przekazywania sygna³ów pomiêdzy komórkami uk³adu nerwowego. Miliony komórek nerwowych mózgu cz³owieka tworz± niezwykle skomplikowan± sieæ neuronaln±. Komórki tej sieci ³±cz± siê specjalnymi wypustkami w miejscach, które nosz± nazwê synaps. B³ony komórkowe neuronów tworz±cych synapsê s± rozdzielone przez w±sk± szparkê - szczelinê synaptyczn±. Pobudzona komórka nerwowa wydziela do szczeliny synaptycznej cz±steczki neuroprzeka¼ników, które ³±cz± siê z receptorami umieszczonymi w b³onie drugiej komórki nerwowej i uruchamiaj± szlak przekazywania sygna³u. W ten sposób neurony porozumiewaj± siê ze sob±. Zrozumienie mechanizmu przesy³ania impulsów w uk³adzie nerwowym ma ogromne znaczenie dla biologii i medycyny. Odkrycia trzech nowych laureatów Nobla pozwoli³y naukowcom lepiej zrozumieæ dzia³anie mózgu i stworzyæ nowe leki, które s± z powodzeniem stosowane w terapii chorób neurologicznych i psychiatrycznych. Arvid Carlsson Arvid Carlsson (pracownik Wydzia³u Farmakologii uniwersytetu w Gothenburg) udowodni³, ¿e dopamina jest wa¿nym neuroprzeka¼nikiem wykorzystywanym przez niektóre komórki mózgu do przekazywania sygna³ów w synapsach. Wcze¶niej uwa¿ano, ¿e dopamina s³u¿y tylko do produkcji innego neuroprzeka¼nika - noradrenaliny. Carlsson odkry³, ¿e niektóre czê¶ci mózgu (przede wszystkim pewne zwoje podstawne) s± szczególnie bogate w dopaminê, chocia¿ nie wytwarzaj± du¿o noradrenaliny, i stwierdzi³, ¿e w tych miejscach to dopamina mo¿e byæ g³ównym przeka¼nikiem synaptycznym. ¯eby to udowodniæ, podawa³ zwierzêtom laboratoryjnym zwi±zek chemiczny, który wywo³uje zaburzenia w magazynowaniu ró¿nych neuroprzeka¼ników (miêdzy innymi dopaminy). Okaza³o siê, ¿e zwierzêta poddane dzia³aniu tej substancji trac± zdolno¶æ do wykonywania spontanicznych ruchów. L-dopa (zwi±zek chemiczny, z którego w mózgu powstaje dopamina) przywraca³a tym zwierzêtom prawid³owe funkcje ruchowe.

51. Nobel E-Museum 2000 Arvid Carlsson, paul greengard, Eric R. Kandel. 1999 - Günter Blobel. Searchthis site. Marie Curie was the first to receive a nobel Prize twice. http://nobel.sdsc.edu/

2002 - Raymond Davis Jr., Masatoshi Koshiba, Riccardo Giacconi 2001 - Eric A. Cornell, Wolfgang Ketterle, Carl E. Wieman 2000 - Zhores I. Alferov, Herbert Kroemer, Jack S. Kilby 1999 - Gerardus 't Hooft, Martinus J.G. Veltman ... 1998 - John Hume, David Trimble Find a Laureate Search this site "Nonviolence is a powerful and just weapon. Indeed, it is a weapon unique in history, which cuts without wounding and ennobles the man who wields it." Laser Challenge The Transistor Chirality - Chemistry 2001 Pavlov's Dog ... Tell us what you think about this site! Last modified April 17, 2003 The Official Web Site of The Nobel Foundation

52. CNN.com - Brain Disorder Pioneers Win Nobel Prize - October 9, 2000 The 50strong nobel Assembly, at Sweden's Karolinska Institute, which makes theaward, said Arvid Carlsson, paul greengard and Eric Kandel will share a prize http://www.cnn.com/2000/WORLD/europe/10/09/sweden.nobel/

world europe Editions myCNN ... Feedback CNN Sites CNN CNN Europe CNNfn CNNSI myCNN CNNfyi AllPolitics Languages Search CNN.com CNNSI.com CNNfn.com The Web WORLD TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Gates pledges $100 million for AIDS Davos protesters face tear gas ... MORE TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Davos protesters face tear gas MORE ... MORE MARKETS 4:30pm ET, 4/16 DJIA NAS SPORTS Jordan says farewell for the third time ... LOCAL EDITIONS: CNN.com Europe change default edition MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists Enter your address: DISCUSSION: chat feedback CNN WEB SITES: CNNfyi.com CNN.com Europe AsiaNow Spanish ... Korean Headlines TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: CNN anchors transcripts Turner distribution SITE INFO: help contents search ad info ... jobs WEB SERVICES: Brain disorder pioneers win Nobel Prize STOCKHOLM, Sweden

53. CNN.com - IT And Plastics Pioneers Win Nobel Prizes - October 10, 2000 The announcement follows the award of the nobel Prize for Physiology or Arvid Carlsson,paul greengard and Eric Kandel's research on how brain cells transmit http://www.cnn.com/2000/WORLD/europe/10/10/sweden.nobel/

world europe Editions myCNN ... Feedback CNN Sites CNN CNN Europe CNNfn CNNSI myCNN CNNfyi AllPolitics Languages Search CNN.com CNNSI.com CNNfn.com The Web WORLD TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Gates pledges $100 million for AIDS Davos protesters face tear gas ... MORE TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Davos protesters face tear gas MORE ... MORE MARKETS 4:30pm ET, 4/16 DJIA NAS SPORTS Jordan says farewell for the third time ... LOCAL EDITIONS: CNN.com Europe change default edition MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists Enter your address: DISCUSSION: chat feedback CNN WEB SITES: CNNfyi.com CNN.com Europe AsiaNow Spanish ... Korean Headlines TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: CNN anchors transcripts Turner distribution SITE INFO: help contents search ad info ... jobs WEB SERVICES: IT and plastics pioneers win Nobel prizes STOCKHOLM, Sweden Three Russian and U.S. scientists and inventors have won the 2000 Nobel Prize in physics for their work in laying the foundations of information technology.

54. La Repubblica/cultura_scienze Il Nobel Per La Medicina A 3 Translate this page il primo nobel per la medicina del Terzo Millennio a tre pionieri degli studi sulcervello. Arvid Carlsson, dell'università di Goteborg, paul greengard, della http://www.repubblica.it/online/cultura_scienze/nobel2000/medicina/medicina.html

55. ABCNEWS.com : Trio Share Medicine Nobel Arvid Carlsson, paul greengard and Eric Kandel won the nobel Prize in medicinefor their discoveries concerning how messages are transmitted in the nervous http://abcnews.go.com/sections/living/DailyNews/nobel001009.html

December 17, 2000 Good Morning America World News Tonight Downtown Primetime ... ABCNEWS.com GO TO: Select a Topic Health Index HOMEPAGE HEALTH FEATURE Swedish Professor Arvid Carlsson, of the University of Goteborg, Sweden, is seen in this 1969 file photo. Carlsson was named the 2000 Nobel Prize winner in medicine, together with Americans Paul Greengard and Eric Kandel. (AP Photo) The Prize Trio Share Medicine Nobel The Associated Press S T O C K H O L M, Oct. 9 The three Nobel laureates will share the $915,000 prize for their pioneering discoveries concerning one way brain cells send messages to each other, according to the award citation. Carlsson, 77, is with the University of Goteborg in Sweden, Greengard, 74, is with Rockefeller University in New York and Kandel, 70, is an Austrian-born U.S. citizen with Columbia University in New York. More to Come The awards culminate Friday with the coveted peace prize in Oslo, Norway. Greengard was awarded for his discovery of how dopamine and other chemical messengers shuttle messages between brain cells. Kandel was cited for his research on the biology of memory, showing the importance of changes in the synapse, a tiny gap between brain cells where messages are transmitted. Suspense Over Literature The Swedish Academy, which traditionally keeps the date of the literature prize secret until a couple days before it announces the winner, has not set a time yet, but it is always a Thursday, usually in October.

56. Premio Nobel De Medicina - Wikipedia Translate this page enlace http//www.nobel.se/medicine/laureates/index.html. 2001 Leland H. Hartwell,R. Timothy Hunt, paul M. Nurse 2000 Arvid Carlsson, paul greengard, Eric R http://es.wikipedia.org/wiki/Premio_Nobel/Medicina

Portada Cambios Recientes Edita esta página Historia Páginas especiales Preferencias de usuario Mi lista de seguimiento Cambio Recientes Subir una imagen Lista de imágenes Usuarios registrados Estadísticas del sitio Artículo aleatorio Artículos huérfanos Imágenes huérfanas Artículos populares Artículos más solicitados Artículos cortos Artículos largos Artículos nuevos Todas las páginas (alfabético) Direcciones IP bloqueadas Página de mantención Fuentes externas de libros Versión para imprimir Discusión Registrase/Entrar Ayuda Premio Nobel de Medicina (Redirigido desde Premio Nobel/Medicina Ver enlace: http://www.nobel.se/medicine/laureates/index.html Leland H. Hartwell R. Timothy Hunt Paul M. Nurse ... Harold E. Varmus Sir James W. Black Gertrude B. Elion George H. Hitchings Susumu Tonegawa ... Barbara McClintock for transposon work. Sune K. Bergström Bengt I. Samuelsson John R. Vane Roger W. Sperry ... Earl W. Sutherland, Jr. Sir Bernard Katz Ulf von Euler Julius Axelrod Max Delbrück ... Feodor Lynen Sir John Carew Eccles Alan Lloyd Hodgkin Andrew Fielding Huxley Francis Harry Compton Crick ... Georg von Békésy Sir Frank Macfarlane Burnet Peter Brian Medawar Severo Ochoa Arthur Kornberg ... Dickinson W. Richards

57. Nobel Lectures In Physiology Or Medicine Berzelius laboratoriet, Stockholm Ondemand videos of the lectures Arvid Carlsson,paul greengard, Eric R Kandel. Copyright© 2000 The nobel Foundation http://www.mednobel.ki.se/lecture2000.html

The 2000 Nobel Lectures in Physiology or Medicine A Half-Century of Brain Neurotransmitter Research: Impact on Neurology and Psychiatry by Arvid Carlsson The Neurobiology of Dopamine Signaling by Paul Greengard Molecular Biology of Memory Storage: A Dialogue Between Genes and Synapses by Eric Kandel Friday, December 8, 2000 between 1:50 and 4:15 p.m., at Karolinska Institutet, Berzelius laboratoriet, Stockholm On-demand videos of the lectures: Arvid Carlsson Paul Greengard Eric R Kandel

58. Nobel Prize Laureates Dr. paul greengard (see Figure 6) received the nobel Prize for physiology and medicinefor his work in signal transduction in the nervous system. The nobel http://www.afrlhorizons.com/Briefs/Mar02/OSR0109.html

Nobel Prize Laureates The Air Force Office of Scientific Research creates a legacy of Nobel Prize-winning research. AFRL's Air Force Office of Scientific Research, Arlington, VA One of the most highly coveted and recognized awards, the Nobel Prize, recognizes those who contribute significant achievements in the areas of physics, chemistry, physiology or medicine, literature, peace, and economic sciences. The Nobel Foundation was established in 1900 and in 1901 the Nobel Prize became the first international award to be given on an annual basis. Established as outlined in his last will and testament, Dr. Alfred Nobel stated, "...the whole of my remaining realizable estate shall be dealt with in the following way...annually distributed in the form of prizes to those who, during the preceding year, shall have conferred the greatest benefit to mankind." AFOSR funded 26 Nobel Prize laureates in physics, 14 in chemistry, and 6 in physiology and medicine. The selection of Nobel Prize laureates and their respective prize citations readily demonstrates the astute ability of AFOSR program managers to choose world-class researchers to readily address Air Force (AF) requirements and advance AF programs. AFOSR-funded research created many breakthroughs in the area of physics. Drs. Polykarp Kusch and Wills Eugene Lamb shared the 1955 prize for work in "precision determination of the magnetic moment of the electron" and "discoveries concerning the fine structure of the hydrogen spectrum." The early research by these two winners resulted in the development of techniques for microwave interaction with atoms and atomic beams. One important application to the AF, and increasingly within civilian economy, is the cesium beam atomic clock, an essential part of the Global Positioning System (GPS). Without the incredibly accurate time-keeping capabilities of atomic clocks, the GPS would not be possible.

59. Nobel Prize For Medicine 2000 nervous system. This year nobel prize for Medicine has been awardedto a trio, Arvid Carlsson. paul greengard. Eric Kandel. for their http://www.manbir-online.com/news/nobel-2000.htm

Arvid Carlsson July 04, 2002 Nobel prize for Medicine 2000 The Nobel prize for Medicine has been awarded for research which helped doctors inch towards a treatment for Parkinson's Disease. This disease is a tragic disorder of the nervous system. This year Nobel prize for Medicine has been awarded to a trio Arvid Carlsson Paul Greengard Eric Kandel. for their discoveries concerning how messages are transmitted in the nervous system. The three Nobel laureates made pioneering discoveries concerning one way that brain cells pass messages to each other. Sufferers of Parkinson's include Pope John Paul II, Mohamad Ali and screen actor Micheal J. Fox. Their symptoms were in the form of tremor, slow movement or difficulty in speaking. Among the advance cases of Parkinson's the decline in health is even more terrible to witness. The face becomes expression less because of rigidity. The swallowing becomes less frequent, leading to drooling, Depression, Dementia and death. Working separately the trio made discoveries in to chemical signaling in the brain - the minute substances which are used to send a message from one nerve cell to another.

60. Jewish Nobel Prize Winners 1997- Stanley B. Prusiner; 1998 - Robert F. Furchgott; 2000 - paul greengard; http://www.us-israel.org/jsource/Judaism/nobels.html

Jewish Nobel Prize Winners The Nobel Prizes are awarded by the Nobel Foundation of Sweden to men and women who have rendered the greatest service to humankind. Between 1901 and 1995, 663 Nobel Prizes were handed out. Of these, 140 are Jews or people of Jewish descent. Literature 1910 - Paul Heyse 1927 - Henri Bergson 1958 - Boris Pasternak Shmuel Yosef Agnon 1966 - Nelly Sachs 1976 - Saul Bellow Isaac Bashevis Singer 1981 - Elias Canetti 1987 - Joseph Brodsky Nadine Gordimer 2001- Imre Kertesz World Peace 1911 - Alfred Fried Tobias Michael Carel Asser 1968 - Rene Cassin Henry Kissinger Menachem Begin Elie Wiesel Shimon Peres ... Yitzhak Rabin Chemistry 1905 - Adolph Von Baeyer 1906 - Henri Moissan 1910 - Otto Wallach 1915 - Richard Willstaetter 1918 - Fritz Haber 1943 - George Charles de Hevesy 1961 - Melvin Calvin 1962 - Max Ferdinand Perutz 1972 - William Howard Stein Ilya Prigogine 1979 - Herbert Charles Brown 1980 - Paul Berg Walter Gilbert 1981 - Roald Hoffmann 1982 - Aaron Klug 1985 - Albert A. Hauptman

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