Product Description
Many of the cells in our body undergo tightly regulated replication to enable growth to occur and to ensure that damaged or worn out tissues are replaced. Regulation is mediated via many different mechanisms. It is when these mechanisms fail, and regulation is lost, that cancer can result. Recent advances in molecular cell biology have greatly expanded our understanding of the processes and mechanisms which underpin the regulation of cell replication, and what is happening at the molecular level when these fail.

Now in its second edition, The Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics gives a fresh approach to the study of the molecular basis of cancer. Written with the undergraduate student in mind, Lauren Pecorino focuses on how our understanding of the defective mechanisms which drive cancer is leading to the development of new targeted therapeutic agents.

Opening with an overview of the key hallmarks of cancer as a disease state, the book then leads us through the principal components of the regulatory machinery through which cell division is controlled and corrupted with the onset of cancer. Within each chapter, students are shown how this molecular knowledge is being applied to develop new targeted therapeutic strategies.

Ideal for courses in the molecular biology of cancer and cancer biology, The Molecular Biology of Cancer, Second Edition, is an invaluable resource for any student wishing to gain insight into the molecular basis of the disease and formulate possible solutions for its effective control.

New to this Edition


· Updated research


· Three brand new chapters:
- "The Cell Cycle": Gives extended treatment of this central aspect of cancer biology
- "Infections and Inflammation": Focuses on the relationship between infectious agents and inflammation and the onset of cancer
- "The Cancer Industry": Provides an overview of the process through which drugs are developed and tested


· Enhanced coverage of apoptosis


· Over 25 new figures plus a new color plate section


· A new "How do we know that?" feature, in which experimental methods and results are discussed, thus shedding light on how our understanding of cancer biology is developed


· An extended glossary


· A companion website featuring additional resources for both instructors and students:
- For instructors, the site offers figures from the book available to download and a testbank of multiple-choice questions with feedback linked to the book for use in formative or summative assessment
- For students, the website features a web link library as well as hyperlinks to primary literature articles cited in the text ... Read more

Customer Reviews (6)

Excellent update on oncology background, state of the art and specialty
This is the book to review if you are behind on understanding the intricate world of cancer diagnosis, treatment, and some of the causes and origins of cancer.Recently released (2009) this book overviews the entire gamut of identification, treatment, response, and follow up.Perfect for medically-oriented patients, family members, or medical school students.This is NOT a book for the lay public - you need to understand medical terminology and the basics of oncology to fully appreciate.That being said, if you are bent on learning more about this area of medicine, start here!

Introductory in molecular biology of cancer
This is a good book to have if you are looking to have basic information on molecular mechanisms of cancer handy. I specifically bought it for the apoptosis chapter but I think it will be useful on many other subjects

Outstanding, a must read.
Dr. Lauren Pecorino has a genius for the plume to equal her mastery of the subject matter.This book is so well done it deserves to be published in every language and included as University required reading.Highly recommended, it is an outstanding work that held interest from the first page.

Easy to read!
This is a good introduction to this field. The book is easy to read and have good drawings.

An Introduction to the Biology of Cancer - and More
I'm one of those people who like to know how things work - especially if those things are inside my body and are likely to shorten my life span.Since my doctors don't tell me anything, I need other sources, and since the Internet is unreliable, I need a guidebook I can trust.Molecular Biology of Cancer turned out to be just the right book for me.It is also an excellent first book for anyone interested in the molecular biology of cancer.

First, as to technical level: This is very much what one expects in an undergraduate science text, with lots of section headings, lots of diagrams, and lots of boxes highlighting important points.If, like me, you're a non-student and non-scientist but interested in the subject, you'll probably find it very readable.You'll need to have some experience of reading diagrams in which symbols (squares, circles, etc.) represent molecules interacting with each other.And you'll have to be comfortable reading books with plenty of technical language.The terms specific to cancer biology should be no problem since they are well-explained and the terms that are in the glossary are printed in red in the text.You won't need to know anything about the chemistry involved in the molecular interactions (nothing about hydrogen bonding or redox, for example).

Some single-celled organisms can simply grow and divide as fast and as long as their food supply allows.Those that live in colonies must have chemical signals to regulate each cell's growth and activity.Mammals, being enormously more complex, need much more sophisticated communication between cells.That means, of course, that there are many things that can go wrong and many mechanisms to fix things that go wrong.And therefore, there are many things to be considered when diagnosing and treating cancer.Pecorino chooses particular examples to explain general principles.

First, a cell normally doesn't divide until a signal from outside sets off a chain of events that leads to division.An error in this chain, caused by an abnormal protein, can cause the cell to divide without the external signal.Pecorino chooses epidermal growth factor (EGF) to show the working of such a chain.When a cell does start to divide out of control, there are mechanisms which try to stop the reproduction, or to kill the cell.Pecorino focuses mostly on one molecule, called P53, which is involved in a number of such mechanisms and is abnormal in a majority of tumors, including mine.Most cells are fastened in place, so it takes a further abnormality for them to break loose.Since most cancers are caused by abnormal or inappropriately expressed genes, DNA repair and regulation are important.Here, Pecorino mentions the BRCA genes, which turn up often in articles about breast cancer.These are major topics, but there is much more than I can mention in an Amazon-size review.

So many genetic flaws don't show up all at once; a cancer is the product of evolution within one body.This is implicit in Molecular Biology of Cancer, but it is more developed in another book, Darwin in the Genome.(See my review for more info; click above on "See all my reviews".)

Given that there are so many molecular systems involved in cancer, one can see why there are many points at which drugs may inhibit or kill cancer cells.Pecorino points out a number of these.She even flags many these with red target icons, symbolizing potential drug targets.Perhaps by the time a student gets to be a researcher, most of these will be passé - a lot of people are working hard on them -- but her aim is to teach them how to spot potential target molecules and interactions and I think she succeeds.

Cancer can be of interest to people who aren't affected by it because, by showing what happens when things go wrong, it gives new insight into how these systems work in general.For those interested in developmental biology, it shows what happens inside a cell in response to a signal whereas most of the books I've read just mention the cellular interactions.Pecorino also gives examples of how a large variety of molecules may be created by mixing and matching a much smaller collection of simpler molecules or domains; this modularity is important in evolution.

So this book will be of interest to a variety of readers for a variety of reasons.Pecorino is particularly interested in students and hopes that some will be inspired by this book to take up cancer research.I second that and I hope that some will find metastatic prostate cancer to be a worthy field. ... Read more

Product Description

For both volumes:

A comprehensive collection of cutting-edge methods for the molecular and cellular analysis of platelets and megakaryocytes. Volume 1 details basic and advanced techniques for analyzing platelet and megakaryocyte function. The approaches presented for platelet analysis include aggregometry, secretion, arachidonic acid metabolism, procoagulent response, platelet adhesion under static and flow conditions, flow cytometry, and production of microparticles. The techniques for study of megakaryocyte function allow the measurement of specialized structures for platelet production, the appearance of platelet-specific surface receptors, and the increase in ploidy. Volume 2 offers techniques for studying many aspects of signaling in platelets and megakaryocytes, as well as state-of-the-art commentaries on our understanding of these cells. The methods include ligand-binding assays, the study of protein and lipid kinases and phosphatases, the analysis of lipid rafts, and the measurement of intracellular calcium levels. There are also techniques for study of electrophysiological events, nitric oxide signaling, venom proteins, and for the internalization of proteins into platelets through permeabilization. This volume also describes the application of molecular and post-genomic methods for the study of platelets and megakaryocytes.All protocols follow the successful Methods in Molecular Biology™ series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. The two volumes offer novice and experienced cell biologists, hematologists, and clinicians not only a benchmark survey of the field, but also a comprehensive library of proven techniques essential for productive research on platelets and megakaryocytes today.
... Read more

Product Description
This best-selling undergraduate textbook provides an introduction to key experimental techniques from across the biosciences. It uniquely integrates the theories and practices that drive the fields of biology and medicine, comprehensively covering both the methods students will encounter in lab classes and those that underpin recent advances and discoveries. Its problem-solving approach continues with worked examples that set a challenge and then show students how the challenge is met. New to this edition are case studies, for example, that illustrate the relevance of the principles and techniques to the diagnosis and treatment of individual patients. Coverage is expanded to include a section on stem cells, chapters on immunochemical techniques and spectroscopy techniques, and additional chapters on drug discovery and development, and clinical biochemistry. Experimental design and the statistical analysis of data are emphasised throughout to ensure students are equipped to successfully plan their own experiments and examine the results obtained. ... Read more

Customer Reviews (7)

Excellent Review
This is a very good review on the main techniques of biochemistry and molecular biology. Excellent for filling up those gaps that bad teachers left behind.

Tons of Info
It was more than I needed or could use. I tried to contact the seller to see if I could return it, but got no response.

Ok as an intro, but rather irksome
I had purchased this book as part of the required books for a molecular biology techniques class in college.While I did skim through most of it at that time, I hadn't given it my full attention.

Two years later, I've sat down and read the entire book (spare 2 chapters).My reason for doing this was to brush up on what I (hopefully) already knew, expand on my knowledge, and to catch some things I'd surely completely missed.

I do not like how the chapters are written by different authors.I suppose it makes sense in light of certain folks being experts in their respective fields... but isn't this book an intro book?Shouldn't the stuff in this book be "the basics"?I noticed that the style of writing (somewhat organization of thoughts, but mostly the tone/way of talking) varied.I also found more than one topic to be repeated in detail.Oh no, not just "refer to section ___ for more info"... nope... totally repeated.

I hate the organization of the book.I feel like the chapters are out of order.The chapters also, I feel, could have been focused differently to better tackle material.

Also, while a great deal of theory is helpful, I sure wished I'd seen some basic info included for actual benchwork.I wanted to see more of typical concentrations, troubleshooting, controls, etc.Because now I just look at this book and think, hmm... the info in that book I can get for free on the internet, probably faster and more detailed.I don't want to lug that thing around to work, etc.No way.Good for class though, I suppose.At least at the end of each chapter there is a recommendations section for further reading.

One of the best lab books available
I was blown away by this book.That's how good it is.

I'm a microbiology grad student working on my Ph.D. and I have referred to this book on multiple occasions.It covers almost every single type of procedure that a student would do in a life science or biochemistry laboratory.From molecular biology to PCR; from Southern blots to western blots; from electrophoresis to mass spectrometry; from cell culture to microscopy.....this book literally covers it all.Additionally, it covers all of these topics in pretty good detail.Each procedure is not only discussed in terms of how to do it, but also why it works.

Fantastic.Every life science, biochemistry, or health science student should have this as a reference book.

good with an adjunct
this is a very nice book with abundant information.there are few topics which are dealt extraordinarily especially centrifugation,HPLC,electrophoresis etcetera.i have been studying this book from my graduation.initially i used to feel some difficulty with this book,so i studied biopysicaland biophysical techniques by Upadhyaya and Upadhyaya.once i got the clear idea regarding the techniques,i shifted to this book.now i feel this book is very helpful.it is highly recommendedto allbiology students. ... Read more

Product Description
With its acclaimed author team, cutting-edge content, and coverage based on landmark experiments, "Molecular Cell Biology" has earned an impeccable reputation with instructors edition after edition. The new Sixth Edition is the "Molecular Cell Biology" for a new generation, a dramatic revision of the classic text featuring two new co-authors, expanded coverage of immunology and development, and new media tools for students and instructors. ... Read more

Customer Reviews (3)

textbooks
Really happy with fast delivey and soooooooo glad I didn't have to pay bookstore price.

A little hard to read
I have a hard time reading this book. I even prefer to just read my instructor's power point. I don't know if the course is just too deep or the content of the book isn't explained the way that is more readable and fun, but I never had any problems with my general bio classes. I got A's in all of my bio classes. I don't know how will it work out this time. I'm taking molecular bio and genetics.

The Best Book On Molecular And Cell Biology
This book is indeed the best introductory book on molecular and cell biology. It is well written and fully illustrated. This new edition also includes a lot of the most recent information particularly in the areas of signaling, cancer, and stem cells. It is a valuable resource for all students of molecular biology. ... Read more

Product Description
Molecular Biology: Principles of Genome Function offers a fresh, distinctive approach to teaching one of today's most fascinating scientific subjects. Its perspective reflects the challenge of teaching a subject that is in many ways unrecognizable from the molecular biology of the 20th century--a discipline in which our understanding has advanced immeasurably, but about which many intriguing questions remain.

FEATURES:

* A focus on underlying principles--rather than an attempt to offer exhaustive detail--equips students with a robust conceptual framework to which they can add further details from the vast amount of scientific information available today.

* An emphasis on the commonalities that exist between bacteria, archae, and eukaryotes--along with coverage of their differences--provides an accurate depiction of our current understanding of the conserved nature of molecular biology and the variations that underpin biological diversity.

* An integration of key themes and concepts demonstrates how molecular phenomena like chromatin modification and RNA silencing have diverse impacts on genome function. It also helps students to appreciate molecular biology as a unified discipline, with many components and phenomena acting in concert.

* Clear demonstrations of the experimental basis of molecular biology (set off in the text in "Experimental Approach" panels) reflect the central importance of experimental evidence to furthering our understanding of molecular biology. These panels describe pieces of research that have been particularly valuable in elucidating different aspects of the discipline.

* Pedagogical features including full-color, custom-drawn artwork; end-of-chapter summaries; suggested readings grouped by topic; and an extensive glossary of key terms further enhance the text.

* An extensive Companion Website features additional materials for both instructors and students. For adopters of the text: figures from the book, available to download for use in lectures, and "Journal Club," suggested research papers and discussion questions linked to topics featured in the book. For students and instructors: "New and noteworthy"--key highlights from the field, updated for the start of each semester--and a library of three-dimensional models of key molecular structures featured in the book. ... Read more

Product Description

Boiled-down essentials of the top-selling Schaum's Outline series, for the student with limited time

What could be better than the bestselling Schaum's Outline series? For students looking for a quick nuts-and-bolts overview, it would have to be Schaum's Easy Outline series. Every book in this series is a pared-down, simplified, and tightly focused version of its bigger predecessor. With an emphasis on clarity and brevity, each new title features a streamlined and updated format and the absolute essence of the subject, presented in a concise and readily understandable form. Graphic elements such as sidebars, reader-alert icons, and boxed highlights feature selected points from the text, illuminate keys to learning, and give students quick pointers to the essentials.

Customer Reviews (3)

Concise, but brevity causes loss of glossary
I needed a primer for biochemistry and upon Amazon search with "primer biochemistry" I came across this.Honestly, it hasn't proven more helpful that the chapter 1 introduction in my textbook yet.I've given 3 stars because I've yet to see how uniquely this book has supplemented my understanding, especially since there is no glossary for all the vocabulary in bold print.If I don't get something from context, I have to go elsewhere.On the other hand, it is brief, to the point, and inexpensive so I don't rate it less.

Great for review, but not very much cell bio
I love this book! It's so easy to read and it provides a good review for students taking molecular biology. However, I wouldn't recommend it as a resource for someone who is just starting to learn. The writing style assumes that you know the basic concepts already and sometimes skims through material quickly. However, I would have to say that this book is very readable and contains some excellent illustrations.

However, my one complaint is the lack of coverage of cell biology. This book seems, frankly, to be almost all molecular biology. It lacks any sort of discussion about actin, microtubules, and so on. I find that disappointing, but I understand that it's a "quick outline."

Great book for reference and quick brush-up
I bought this book so I would not have to shuffle through the pages of my cell/molucular bio textbook. Although this book was great with having the main concepts, there wasn't much detail. But that is the purpose of the book- to have the main molecular biology topics in a clear and organized manner. For more detail and test questions get the full outline book from the same series. If you just want the info you need to know this book is outstanding! ... Read more

Product Description
A must have for all Biotechnology Students and technicians.It walks readers through the minefield of laboratory calculations, helping to prevent the types of errors which could mean the loss of weeks of work.

Key Features:
* Topics range from basic scientific notations to complex subjects like nucleic acid chemistry and recombinant DNA technology
* Each chapter includes a brief explanation of the concept and covers necessary definitions, theory and rationale for each type of calculation
* Recent applications of the procedures and computations in clinical, academic, industrial and basic research laboratories are cited throughout the text

New to this Edition:
* Updated and increased coverage of real time PCR and the mathematics used to measure gene expression
* More sample problems in every chapter for readers to practice concepts
... Read more

Product Description
The long-awaited new edition of James D. Watson's classic text, Molecular Biology of the Gene, has been thoroughly revised and is published to coincide with the 50th anniversary of Watson and Crick's paper on the structure of the DNA double-helix. Twenty-one concise chapters, co-authored by five highly respected molecular biologists, provide current, authoritative coverage of a fast-changing discipline, giving both historical and basic chemical context. Divided into four parts: Genetics and Chemistry, Central Dogma, Regulation, and Methods. For college instructors, students, and anyone interested in molecular biology and genetics. ... Read more

Customer Reviews (6)

"A Scientific Explanation of What Life Is"
"Molecular Biology of the Gene," James Watson et. al, 5th Edition, CSHL Press, NY 2004, ISBN 0-8053-4635-X, HC 732 pages, includes Preface, Index & inter-active CD-ROM & Website.11 1/4" x 8 3/4".

J.D. Watson authored first three editions (1965-'76), co-authored 4th ('87) & this 5th ('04) with Baker, Bell, Gann, Levine & Losick.CD works in Windows, but Mac OS X needs Classic for some sections (CHIME).This treatise has 21 chapters divided into 5 major parts: I-Chem.& Genetics, II-Genome Maintenance, III-Genome Expression, IV-Regulation and V-Methodologies.

The discourse best assumes readers to have both core & some advanced study in biology, chemistry, physics & genetics. It is a tutorial & reference manual with detailed covering of history of genetics, Mendelian heredity, elucidation & clarificaion of double helix, Crick's central dogma 1956, genetic code, weak & high-energy bonds, protein structure, conformation, modularity & domains, allostery, topologies, RNA structure, chromosomal sequence & diversity, duplication, chromatin structure & regulation, nucleosome assembly, DNA polymerase, binding & unwinding, replication error & repairs, DNA damage, recombination, transposition, transciption, splicings, shuffling, ribosomes, gene regulation in pro- & eu-karyotes, embryogenesis of Drosophila, genome evolution & methodologies for phage, bacteria, yeast, fly & mouse.

A formidable and now classic text fittingly entrusted to an elite working group in the US, UK and Canada.Most comforting is the liberal use of diagrams on essentially every page & the interactive CD.

Am Studying for the Biochemistry GRE - This book is golden
I got this book to assist for my prep for the Biochemistry GRE - I know a lot about Biology.So this is a great Book - First, It is very readable - I was surprised I was not able to put it down and knocked off 100 pages in record time.Besided that - it is enjoyable and not dull and boring - Second, The great experiments are given and insight into the science reasoning behind them also. This book makes the discover of genetics, DNA, RNA and protein building come alive. Third, this book is very current with research and cites the papers and journals where the important biology, Genetic, molecular & cell biology was published.That alone would save you the time to research and site these for your own research.Lastly, the pictures and recollections of the experimenters and "who knew who" are a total hoot.

Great Book
This book is an awesome teaching guide but the real prize goes to the CD and animations. Where a subject might be a bit hazy in the text, the flash animations on the CD are clear and concise.

Good book
Some books are just very well written-this is one of them!

I like that they leave space in the margin to write notes. Organized more like a book you can read in chapters compared to the Lewin Genes text. Concise and up to date.

Good disc included with lots of great animations.

Don't buy this book
Buy this book if you are really unintelligent and knows virtually nothing about biology.Really.if you are the person who wants to learn, find an alternative book. ... Read more

Product Description
Recent advances in the biosciences have led to a range of powerful new technologies, particularly nucleic acid, protein and cell-based methodologies. The most recent insights have come to affect how scientists investigate and define cellular processes at the molecular level. Molecular Biomethods Handbook, 2nd Edition expands upon the techniques included in the first edition, providing theory, outlines of practical procedures, and applications for a range of techniques. Part A of the book describes nucleic acid methods, such as gene expression profiling, microarray analysis and quantitative PCR. In Part B, protein and cell-based methods are outlined, in subjects ranging from protein engineering to high throughput screening. Written by a well-established panel of research scientists, Molecular Biomethods Handbook, 2nd Edition provides an up to date collection of methods used regularly in the authors’ own research programs. This book will prove to be an invaluable reference for those engaged in or entering the field of molecular biology, and will provide the necessary background for those interested in setting up and using the latest molecular techniques. ... Read more

Product Description

In recent years, single nucleotide polymorphisms have received increased and special attention in a rapidly developing field of personalized medicine and drug treatment. Comprising more than eighty percent of all known polymorphisms, single nucleotide polymorphisms (SNPs) are primarily responsible for phenotypic differences between individuals, and have been suggested to affect the development of diseases in humans and the response to drug treatment and environmental stress. In Single Nucleotide Polymorphisms: Methods and Protocols, Second Edition, expert researchers explore the latest advances in this area, highlighting the substantial progress that has been made in SNP genotyping, examining recent developments in high-throughput genotyping approaches, and exploring our new understanding of the impact of SNPs on gene function. Chapters address the impact of SNPs on phenotype, examine SNP databases, look at methods that have been applied for SNP bioinformatics discovery and analysis, and discuss advanced experimental approaches used for SNP detection. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls.

Current and innovative, Single Nucleotide Polymorphisms: Methods and Protocols, Second Edition is an essential guidebook for individual researchers as well as institutions and companies working in the field.

Product Description

While ornamental plants are produced mainly for their aesthetic value, the propagation and improvement of quality attributes such as leaf types, flower colour and fragrance, longevity and form, plant shape and architecture, and the creation of novel variation are important economic goals for the expanding ornamental industry. In Protocols for In Vitro Propagation of Ornamental Plants, leading researchers in the field compile step-wise protocols for rapid plant multiplication and in vitro storage of major commercially viable ornamental plants. Divided into two sections, Section A contains chapters mainly on micropropagation of cut and pot flowers with detailed protocols involving in vitro culture-explants, medium preparation, detailed medium table, shoot initiation and proliferation, root induction, in vitro plant hardening, and field transfer, and Section B delves into reviews on topics such as in vitro production of sweet peas, the status of transgenics in ornamental plants, in vitro conservation, the status of floriculture in Europe, azalea phylogeny, and thin cell layers. As part of the highly successful Methods in Molecular Biology™ series, chapters include introductions to their respective topics, lists of the necessary materials, step-by-step laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.

Comprehensive and clear, Protocols for In Vitro Propagation of Ornamental Plants presents key techniques that will be of great use to floriculturists, researchers, commercial companies, biotechnologists, and students dealing with ornamental plants.

Product Description
'Provides comprehensive detail on the various aspects of particular molecules involved in the phases of injury and repair and thecellular movements and processes....This is an excellent referencebook for libraries serving biology and health science clientele andfor workers in this field of research.' --AmericanScientist, from a review of the First Edition All chapters of thissecond edition have been completely revised and expanded--especially the chapters on growth factors and extracellular matrix molecules. New chapters discuss provisional matrix proteins, extracellular matrix receptors, and scarring versus nonscarring wound healing. ... Read more

Customer Reviews (1)

A very comprehensive book. Well worth the price.
This book is pretty amazing. All the molecular and cellular mechanisms and applications involved in wound repair are discussed in depth. The chapters are filled with so much detail in this area that it would be a must-have resource for any researcher or student in this field. ... Read more

Product Description
Recently expanded to 2 volumes, Short Protocols in Molecular Biology, Fifth Edition, provides condensed descriptions of more than 700 methods compiled from Current Protocols in Molecular Biology. Includes new chapters on chromatin assembly and analysis, nucleic acid arrays, generation and use of combinatorial libraries, discovery and analysis of differentially expressed genes in single cells and cell populations.

The book is specifically designed to provide quick access to step-by-step instructions for the essential methods used in every major area of molecular biological research

Short Protocols in Molecular Biology, Fifth Edition is an authoritative and indispensable guide for all life scientists, researchers, and students at the graduate and advanced undergraduate level

Expanded to 2 volumes. ... Read more

Customer Reviews (5)

no longer short
I used a previous edition of this book in graduate school, and it was an excellent resource.Covering a broad range of protocols in a complete but concise manner, it was a single albeit fat volume that was portable and reasonably priced. In comparison to Maniatis and the full version of CP, this edition remains less extensive and less expensive, however in expanding to 2 volumes it has lost the advantage of portability that was (what I thought) really set it apart from others.The price of this edition has also increased to the point where the value of owning a personal copy has become highly questionable.

an excellent brief reference book
This is a well-organized, clear, short reference work.Well done

The (little) Red book...
Here is the little red bok.
If the big one is too expensive for you, you can always buy this. You'll find inside all the important protocols and data for molecular biology.It's up to date, and clearly presented.
Try it, and then buy the big one!

A very good reference manual
This book is an essential tool for people in the scientific field such as Molecular Biology (obviously), Biochemistry, and Neuroscience. It is comprehensive and up-to-date as far as the techniques are concerned. It isgood value in a sense that you don't have to buy the whole "CurrentProtocols Series" which costs an arm and a leg if you do. Althoughnowadays, a lot of "kits" are commercially available, thetechniques found in this book explain principles and provide differentalternatives suited for your needs. Molecular Cloning by Maniatis et al.,although needs updating, is still a helpful reference in my opinion and itcomplements this book.

A Must-Have for any Molecular Biologist...
I originally bought this book as a secondary source of information (Maniatis has ben my bible now for a few years...) but as time has progressed I have found myself using this book more and more.Theprotocols are easy to follow, logically placed, give enough information soyou understand what it is you are doing, are up to date, and are all in onevolume.Yes, this has effectively replaced my copy of Molecular Cloning(which is indesperate need of an update).Great job! ... Read more

Product Description

Quantum Dots captures many diverse applications enabling utility in biological detection. Organized into five parts, the first two parts cover the use of QDs in imaging fixed and living cells (and tissues). Protocols are included for using QDs in routine as well as enabling applications. Part 3 shows early efforts aimed at using QDs in live animals. The final two parts demonstrate the versatility of QD technology in existing assay technology.

Customer Reviews (1)

A good guide to qdots
This book is a good guide to qdots. Dealing with all the basics, giving a good idea about this new segment of the science. I miss only one thing: double or multiple labeling techniques with streptavidin-conjugated qdots. ... Read more

Product Description
This book covers the cellular level including cell communication, DNA organization, and cytoskeletal development and function. ... Read more

Product Description
High-Yield Cell and Molecular Biology, Third Edition provides the essential information needed for USMLE Step 1 review and course study. It covers current cell and molecular biology techniques and principles with a clinical focuswhat a physician needs to know to understand, diagnose, and treat human disease. Molecular biology is often taught within various courses such as biochemistry, microbiology, and histology; thus, a consolidated review book in molecular biology is especially helpful in preparing for the USMLE Step 1. ... Read more

Customer Reviews (5)

Definitely not worth the hype
I bought this book to study for the USMLE Step 1 exam because of recommendations that I read on [...]. The book is currently out of print, and many people will try to buy this book for exorbitantly high prices in some cases. It isnot worth any more than cover price in my opinion. I admittedly have a solid background in Genetics from undergrad and research but I probably have the same background in Molecular Biology as every other US med student and I don't think I really learned anything from this book that I didn't already know, or at least anything I wouldn't have learned from UWorld and First Aid. If you struggle with these subjects, this book presents the concepts very clearly and concisely, but if you are not particularly weak in this area, I don't think this book is worth the extra money that it sometimes costs.

Better than the newer edition
This book is much more concise than the new edition and is perfect review for USMLE.

NOT WORTH IT
This book is ok if you are struggling in this area, but it really isn't necessary.It isn't even a highly tested subject.DONT buy it here for $50 or more. It is not worth it. If you think you need it, try first getting it from another student.I sent an email to my school's listserve and somebody sold it to me for $25.Give it a try....

Not bad is a quick kill
To get the quick and fast H.Y. facts for the boards this is the one! Its shorter and to the point in comparison to BRS. Note this is not a good book for class only for the Boards

Very High Yield!
High yield cell and molecular biology is exactly what it says, and from the outset doesn't pretend to be anything else. "Lean efficient text" says the blurb, "Study guides with the barest essentials". These words certainly comforted me after reading the somewhat ominous title! The text is compact, with clear and helpful diagrams illustrating and clarifying the most difficult concepts in the book. The style is in fact very much the same as I might choose to write own revision notes, with chapters divided into sub-titles, and those into bullet points. Key words are emboldened, so it is possible to absorb a page by only scanning the bold type; useful if you are caught short when preparing for an exam and need the facts quickly! There is a smattering of clinical examples throughout, and descriptions of procedures such as PCR, which both help anchor your thoughts of the sometimes abstract nature of the subject. Being a molecular biology book it is biased toward genetics, and as this is a confusing area for many students (including me), this will help if your genetics lectures tend to sail several meters over your head. On the downside, the economic nature of the text and the no-frills nature of the diagrams mean that it is not a particularly colourful or engaging read in it's own right. This is also positive, meaning that it is easier to extract information quickly than would be possible from a more bulky text. It is clearly meant to be dipped into, rather than read cover-to-cover. Realistically though, who would read a textbook cover-to-cover?People who will benefit from this book will be pre-clinical medical students, those intercalating a BSc in clinical science or genetics, doctors requiring an up-to-date review, or other students of biomedical science. This should not be your only textbook on cellular biology and genetics, but will serve as the perfect revision tool when exams sidle up too close for comfort. ... Read more

Product Description
The third edition of The Neuron provides a comprehensive first course in the cell and molecular biology of nerve cells. The first part of the book covers the properties of the many newly discovered ion channels that have emerged through mapping of the genome. These channels shape the way a single neuron generates varied patterns of electrical activity. Next are covered the molecular mechanisms that convert electrical activity into the secretion of neurotransmitter hormones at synaptic junctions between neurons. The second part of the book covers the biochemical pathways that are linked to the action of neurotransmitters and that can alter the cellular properties of neurons or sensory cells that transduce information from the outside world into the electrical code used by neurons. The final section reviews our rapidly expanding knowledge of the molecular facters that induce an undifferentiated cell to become a neuron, and then guide it to form appropriate synaptic connections with its partners. This section also focuses on the role of ongoing experience and activity in shaping these connections, and finishes with an account of mechanisms thought to underlie the phenomena of learning and memory. New for the Third Edition: This is a thoroughly revised and expanded edition (60 pages longer) and features a new 8-page, 4-color insert as well as the following changes: 1. The mapping of the human genome and that of other species has led to the discovery of numerous new proteins that regulate the excitability, development, and function of neurons. These have been incorporated into the new edition in nearly all of the chapters. 2. The first section of the book, which deals with neuronal excitability, has been reorganized to make it more readable for those students with less background in physical sciences. A new chapter has been added to this section to allow the incorporation of new information on ion channel structure and on the role of channel auxiliary proteins in modulating neuronal excitability. 3. A new chapter, "The Birth and Death of Neurons," has been added to the last section. In addition to covering new discoveries about the early development of neurons, this chapter describes the recent discovery that new neurons are continually being formed in certain parts of the adult mammalian brain. It also describes research on stem cells, which holds therapeutic potential for the repair of damaged or diseased brain tissue. 4. The use of imaging technologies in the study of the brain has expanded enormously in the past few years. The new edition describes some of these new approaches. Moreover, the introduction of full color plates now allows many new images to be presented in their original form. ... Read more

Customer Reviews (6)

Great book for my cellular biology of the nervous system class
Excellent textbook, explains very well the terms it presents while on the same time is a very easy to read book. It seemed much easier for me to read and comprehend what we learned in class with "the Neuron" in comparison to our designated textbook, which was also very good but less enjoyable.

Great book
I've really enjoyed this book so far. It's by far the best neuro molec book out that I've got my hands on.

A beautiful text
This is one of the few molecular neurobiology textbooks available to the serious student. Overall, it is a very well written text, up to date, and quite detailed.

There is one weird quality about the book, however: the authors have not directly referenced statements in the book, as you would expect to find in any good advanced textbook in a scholarly field. They have instead written a bibliography at the very end, consisting of "Recommended Reading" and "References" for each chapter. I am unsure what criteria they used to differentiate the two.

Other than this minor point however, it's a first rate buy. The authors deserve several pats on their backs.

Neuron details
The molecular biology of the neuron is considered, from its electrical properties, synapses, differentiation, axon pathfinding, to chapters concluding with behavior and memory. Well written and includes easy to follow schematic diagrams, this reference is suitable for the motivated general reader.

Great book on all levels
"The Neuron" was a fantastic book to read. It served as a perfect mesh between a textbook and a novel. The book was written in plain english so anyone could enjoy it. The concepts discussed ranged from elementary to advanced which provided a nice progression to more complicated things. This book is a must read for anyone interested in neuroscience. ... Read more

Product Description
The author received the 2009 Outstanding Faculty Award, the Commonwealth of Virginia's highest honor for faculty, in January 2009.

More accessible to beginning students in the field than its encyclopedic counterparts, Fundamental Molecular Biology provides a distillation of the essential concepts of molecular biology, and is supported by current examples, experimental evidence, an outstanding art program, multimedia support and a solid pedagogical framework. The text has been praised both for its balanced and solid coverage of traditional topics, and for its broad coverage of RNA structure and function, epigenetics and medical molecular biology.

• Focuses primarily on eukaryotic examples but includes key comparisons with prokaryotic organisms where it is appropriate
• Includes all-original artwork providing the clearest possible insight into complex concepts. All artwork is available online and on CD-ROM
• Supplemented by outstanding student and instructor media resources including a CD-ROM that comes with every book and an interactive website at www.blackwellpublishing.com/allison featuring all artwork, animations of key processes, and useful student comprehension material
• Pedagogical boxes throughout explain additional concepts and topics in molecular biology:
  -TOOLS BOXES explore key experimental methods and techniques in molecular biology
  -FOCUS BOXES offer more detailed treatment of topics and delve into experimental strategies, historical background and areas for further exploration
  -DISEASE BOXES illustrate key principles of molecular biology by examining diseases that result from gene defects

Visit www.blackwellpublishing.com/allison to access helpful student and instructor resources online.

Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file. ... Read more

Customer Reviews (4)

Not the best molecular biology book out there
I took a molecular biology course with this text book, and did not like this book at all. The book goes into much detail at some parts such as the specific types of co-factors and co-enzyme names, without devoting to explaining what the general material. If this is your first molecular bio class, I would stay away from this book. It is not only intimidating to approach, but confusing to read.

Great Book
This is literally the best biology textbook I have encountered. Not only is it very appropriate for the class I took, but it has been a great reference for me since then. It really helps that it has anything you could ever want to know about molecular biology. Very comprehensive and comprehensible.

Fundamental Molecular bilogy (very good condition)
I am happy the book(Fundamental Molecular Biology)that I bought is in good condition(like new) and the shipping was fast.I would like to recommend books from this seller.

Very Good
This is a great textbook.It is literally filled with helpful pictures and diagrams that help explain a number of confusing procedures and processes. It is only the first edition, so it can only get better. ... Read more

Product Description
In this second volume of a three-volume set (updating the seminal 1981 monograph The Molecular Biology of the Yeast Saccharomyces), the emphasis is on gene expression. A continuing theme of these monographs has been the extent to which basic biological processes have been conserved in the eukaryotic ... Read more