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This volume is produced from digital images created through the University of Michigan University Library's large-scale digitization efforts. The Library seeks to preserve the intellectual content of items in a manner that facilitates and promotes a variety of uses. The digital reformatting process results in an electronic version of the original text that can be both accessed online and used to create new print copies. The Library also understands and values the usefulness of print and makes reprints available to the public whenever possible. This book and hundreds of thousands of others can be found in the HathiTrust, an archive of the digitized collections of many great research libraries. For access to the University of Michigan Library's digital collections, please see http://www.lib.umich.edu and for information about the HathiTrust, please visit http://www.hathitrust.org ... Read more

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This digital document is an article from Science News, published by Thomson Gale on December 8, 2007. The length of the article is 599 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Sickle save: skin cells fix anemia in mice.(This Week)
Author: B. Vastag
Publication: Science News (Magazine/Journal)
Date: December 8, 2007
Publisher: Thomson Gale
Volume: 172Issue: 23Page: 355(1)

Distributed by Thomson Gale ... Read more

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Chapters: Leukemia, Lymphoma, Anemia, Acute Myeloid Leukemia, Sickle-Cell Disease, Multiple Myeloma, B-Cell Chronic Lymphocytic Leukemia, Acute Lymphoblastic Leukemia, Pernicious Anemia, Chronic Myelogenous Leukemia, Polycythemia Vera, Juvenile Myelomonocytic Leukemia, Hemolytic Anemia, Thrombocytopenia, Aplastic Anemia, Large Granular Lymphocytic Leukemia, Megaloblastic Anemia, Hepatosplenic T-Cell Lymphoma, Warm Autoimmune Hemolytic Anemia, Lymphocytopenia, Leukocytosis, Pancytopenia, Left Shift, Hypersegmented Neutrophil, Normocytic Anemia, Macrocytosis, Perls' Prussian Blue, Acute Myeloblastic Leukemia. Source: Wikipedia. Pages: 210. Not illustrated. Free updates online. Purchase includes a free trial membership in the publisher's book club where you can select from more than a million books without charge. Excerpt: Acute myeloid leukemia (AML), also known as acute myelogenous leukemia, is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells. AML is the most common acute leukemia affecting adults, and its incidence increases with age. Although AML is a relatively rare disease, accounting for approximately 1.2% of cancer deaths in the United States, its incidence is expected to increase as the population ages. The symptoms of AML are caused by replacement of normal bone marrow with leukemic cells, which causes a drop in red blood cells, platelets, and normal white blood cells. These symptoms include fatigue, shortness of breath, easy bruising and bleeding, and increased risk of infection. Although several risk factors for AML have been identified, the specific cause of the disease remains unclear. As an acute leukemia, AML progresses rapidly and is typically fatal within weeks or months if left untreated. AML has several subtypes; treatment and prognosis varies among subtypes....More: http://booksllc.net/?id=4323952 ... Read more

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Sickle Cell Disease and How It Is Inheritied * Who Has Sickle Cell Disease and Why * Inside the Red Blood Cell * Possible Effects of Sickle Cell Disease * How to Care for People with Sickle Cell Disease * Planning a Family * Searching for a CureAlthough more is known about sickle cell disease than about any other inherited disease, no cure for it exists. It is of enormous biological, social, and historc importance. In America alone, about one in 375 who are of American ancestry is born with sickle cell disease. Since it was first identified in medical literature almost a century ago, its effects have been traced worldwide.This book was written for those who have the disease, their families, the carriers of the sickle cell gene, teachers, care givers, and those who wish to update their information. Included is discussion of the variety of symptoms in both children and adults as well as the emotional aspects of the disease. Of particular interest is a chapter on the care, especially the home care, of those who are affected. Here the reader is made aware of current research, the commitment to finding a cure, and the hope that one ultimately will be devised.Miriam Bloom is a geneticist who has written extensively on health issues for the federal government. A former senior editor for the "Journal of the National Cancer Institute", she is president of SciWrite, an international biomedical writing and editing service. ... Read more

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I did not understand much about the disease until I read this book. This was an excellent source. ... Read more

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Sickle cell disease is a complex disease with a genetic mutation producing a wide variety of manifestations. It is of great public health importance nationally and internationally. While the conclusions of this study support the generally accepted views on the disease, the book provides the most recent information and state-of-the-art knowledge of the subject. The book is unique in that it presents the genetic, molecular, cellular, metabolic, rheologic, clinical, diagnostic, therapeutic, and psychosocial dimensions of sickle cell disease. Its synthesis of micro to macro, molecular to cellular, individual to social relationships provides a comprehensive study of sickle cell disease. ... Read more