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Univ. of Cincinnati, OH. Text providing updated additional basic and practical knowledge on the acute leukemias beyond the French-American-British (FAB) classification. Includes halftone and color slides and tables. For the diagnostician and researcher. ... Read more

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This volume covers current problems in research andtreatment of leukemias. The characterization of leukemiccells and the evalualtion of their functionare importantthemes with the first hints emerging of the possibility ofrelating them to the intensity of treatment required. Thecytokines, responsible for the cooperation between cells,are also of great importance.The beginning of therapeuticapplications are furthermore demonstrated.Not only are the cytokines themselves very interesting, butalso the application of cells producing cytokines accordingto therange of macrophages found. The emphasis oncell-to-cell relationship isthus a main topic of the book.Furthermore, other treatments, such as bonemarrowtransplantation and interferon therapy play an importantpart as well as the latest results of chemotherapy.A further essential area coveredis the diagnosis andtherapy of chronic myeloproliferative disease. ... Read more

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Hardbound. ... Read more

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An international roster of field-leading experts delivers the seventh edition of the definitive textbook, LEUKEMIA. This classic provides comprehensive guidance on all aspects of leukemia, from etiology and biology to clinical features and therapy. This edition now also provides the molecular basis of several leukemias. It reflects the most exciting period of research in the field in a quarter century, and features information on molecular biology and molecular genetics, as well as biological therapy. ... Read more

Customer Reviews (1)

Tips for life during and after diagnosis
Basic consumer health information covers both adult and childhood leukemias in Leukemia Sourcebook, a fine title which ranges from diagnosis to alternative treatments, staging, and tips for life during and after diagnosis. Add a section of additional resources and you have an important health reference any comprehensive health collection should add. ... Read more

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Inside George D. Amromin, M.D.'s Pathology Book
"Pathology of Leukemia" by George D. Amromin, M.D. is a standard cloth-bound hard cover book.It was published by Hoeber, Medical Division of Harper & Row Publishers, New York, Evanston, and London, 1968.365 black & white illustrations.Library of Congress Number 68-10702.No ISBN on or in book.

Why I am reviewing a 1968 book in 2010.Well, partly because I obtained a used copy just a few months ago and have a little time to write about it now.This book has been out of print for decades.The other main reason is I knew the author.I am a friend of one of Dr. Amromin's sons and know his whole family (four sons and one daughter)."George's" wife, the "Elaine" the book is dedicated to was like a second Mom to me for many years.During my early college years (late teens to early twenties), I often would pick through the doctor's home office trash can, picking out technical medical journals to read.As a biology major I found some amazing stuff in his trash!Great cell biology micrographs and electron microscopy in those journals.The medical pathology photography was less "artistic" and somewhat disturbing.I could go on and on.Back to the book.

In its day it was probably a "state of the art" book about its specialty, the pathology of leukemia and even today it is useful as a basic treatis about leukemia and its differential diagnosis.The electron micrographs are great, and actually artistic as photographic art.As are many of the "light" microscopy images.As a biologist and photographer I love micrographs.But of course the book is dated and 1968 is long before the days of recombinant DNA, polymerase chain reaction (PCR) technology, genetic engineering, and the use of computers for medical data analysis. Dr. Amromin's book is mainly a diagnostic text, little is dedicated to the thoeries or causes of cancer(s) per say.Though I did find at least one great quote in a chapter written by an associate, Dr. Raymond L. Teplitz:

"The genetic endowment of the neoplastic cells is of fundamental importance to its perpetuation.A tumor cell cannot assume a dominant status in a population among "normal" cells unless it is better adapted to the environment.Thus, the features of evolution, mutation, and selection may be thought of as at work in the origin and progression of a tumor.To take the view that one or the other must be the starting point for neoplasia may be an oversimplification, a reflection of the manner in which the origin of infectious disease was once viewed.Mutations or gross chromosomal rearrangements may occur at any time through the influence of various agents on chromosomes or cytokinesis.But the resulting cells must survive an environment to which the normal cell is supremely fit.It is clear that most mutations do not survive this challenge.Those that do, must succeed because of greater fitness endowed by the gentic change and/or environmental changes in which the "normal" cell is no longer competitively unassailable."

I found that extremely interesting, especially since it was written in 1968 or before.It sort of treats tissues as an ecological system.I will not go into details here, but I've read some really interesting theory on the etiology of cancers in some of Dr. Amromin's (often with co-workers) journal articles.This book is well worth owning by any oncology pathologist.Dr. Amromin was a brilliant man and I miss him.
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At nineteen years of age SAMANTHA MILES was diagnosed with acute leukaemia and faced an immediate start to intensive and shockingly intrusive treatment. One minute a student sitting an exam, the next in hospital confronting a life-threatening illness. This book is her very frank and personal account of what she had to go through to get back her life. In a down-to-earth, almost objective style she reveals her feelings toward her disease, chemotherapy and bone marrow transplant. She describes the highs and lows of her physical and mental condition and the reader emerges at the end, like her, exhausted but triumphant. Samantha's story creates an awareness of leukaemia, its effect on young people and their families as well as emphasising the need for increased community information. An honest and powerful book of vital interest not only to those in similar situations but also to those who will admire the courage and strength of the author. ... Read more

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While leukemia remains a life-threatening and debilitating form of cancer, recent advances have made treatment of this disease one of the greatest success stories in modern medicine. (20051001) ... Read more

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Leukemia is a malignant disease which continues to play acutting edge role in the discovery of new basic knowledge about themalignant process and about the potential for controlling thesemalignant diseases. Molecular Genetics and Therapy of Leukemia presentscontributions by leading investigators and scientific contributors tosuch topics as chromosome 16, chromosome 5, the BCL-2 gene, 11q23breakpoint leukemias, the p-53 suppressor gene and oncogene,hematopoietic stem cells, cytokines, detection of minimal residualdisease in acute lymphoblastic leukemia, autologous marrowtransplantation, the retinoblastoma gene, allogeneic bone marrowtransplant and chemotherapy of acute lymphoblastic leukemia. ... Read more

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In March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading."Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and printing.This book was created for medical professionals, students, and members of the general public who want to conduct medical research using the most advanced tools available and spending the least amount of time doing so. ... Read more

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Leukemia
The book provides fundamental ,up-to-date information on the chronic leukemias that will allow those interested in these diseases to hone their diagnosticskills in this rapidly expanding area of hematology. ... Read more

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In March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading."Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and printing.This book was created for medical professionals, students, and members of the general public who want to conduct medical research using the most advanced tools available and spending the least amount of time doing so. ... Read more

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Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the Western world. It is also the prototype of B-cell chronic lymphoid malignancies and of their ramifications within the fields of hematology, immunology and oncology. For a long time the Cinderella of lymphoid malignancies CLL has now become the focus of major interest and an increasing number of investigators from different areas, including genetics, molecular biology, basic and applied immunology are becoming actively engaged in the investigation of CLL. Clinicians are considering CLL as a very interesting target of many projects which aim at translating the new and exciting developments of basic science into effective new approaches to the patient.