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This third edition of Leukaemia and Related Disorders represents a quite radical change in structure and emphasis from previous editions. The book previously contained an extensive basic science section, and while all forms of leukaemia are still covered, the basic science has been pared down, with emphasis on clinical management emphasized. The third edition also contains colour plates of blood films. ... Read more

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National Institutes of Health, Bethesda, MD. Reference contains nine new chapters and offers an overview of chronic lymphocytic leukemia from multiple perspectives. Covers all major developments since the previous edition, c1993. Extensive references. Expanded-outline format. ... Read more

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Chronic lymphocytic leukaemia (or "chronic lymphoid leukaemia"), known for short as CLL, is a type of leukaemia in which too many lymphocytes are produced. Although the malignant lymphocytes in CLL may look normal and mature, they are not and these cells may not cope effectively with infection. CLL is the most common form of leukaemia in adults. Men are twice as likely to develop CLL as women. However, the key risk factor is age. Over 75 percent of new cases are diagnosed in patients over age 50. This book presents important research from around the world in this field. ... Read more

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This text is a patient-oriented guide to dealing with leukemia. Questions and answers cover basic questions about the disease such as risk factors and causes; methods of prevention, screening, and diagnosis; available treatments and how to choose among them; and ways of coping with common emotional and physical difficulties associated with the diagnosis and treatment. The authors, a leukemia survivor and a practicing oncologist/hematologist, team up to provide both a doctor's and a patient's perspective in answering these common questions. ... Read more

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The importance of gene therapy is increasing more and more. This book covers both somatic gene therapy of inherited human diseases as well as of cancer, with emphasis on malignancies of the hematopoietic system. Topics include the isolation and development of hematopoietic stem cells, genes involved in development and diseases, methods of gene transfer, carrying out gene transfer, oncogenes and antioncogenes as targets for gene therapy, receptors and their ligands in normal development and diseases, immunology and immunotherapy, radiation biology, clinical leukemias and bone marrow transplantation. ... Read more

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Keith Dorricott is a leukemia survivor.After being diagnosed at a regular medical checkup in 1988,he was given just a few years to live, with no cureavailable. After many rounds of chemotherapy and beingrejected for a bone marrow transplant, in 1997 he was ableto have a transplant to the amazement of his doctors. A yearlater he was declared to be in full remission. In Keith'sown words, "It had God's finger prints all overit."

This book tells his story of the ten-yearordeal and challenges that he faced, and how they wereovercome with the full support of his family, friends andmedical professionals. But above all it is the story of Godat work in this one man's life, to accomplish His ownpurpose.

Keith still enjoys good health. He isnow a retired business executive, living with his wifeSandra in King City, north of Toronto, Canada, and hedevotes a lot of his time to helping other people todiscover the reality of God in their lives. In 2008 he addeda supplement to this book, entitled "Ten YearsLater..."which is included herein. ... Read more

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Hairy cell leukemia has been the subject of much debate during the past forty years. The etiology and pathogenesis of the disease is still unclear, and the origin of the unusual "hairy" B-lymphocyte is still to be clarified with certainty.Nevertheless, clinical advances in the therapy of this disease have resulted in the control and virtual cure of the majority of cases with the disorder.
This volume addresses all aspects of hairy cell leukemia, embracing the history of the disease, morphology, electronmicroscopy, histopathology, biological and immunological aspects, possible etiological environmental links, diagnosis and differential diagnosis and all aspects of modern therapy.
The authors are established specialists in this field and many have been leaders in the investigation and therapy of hairy cell leukemia, contributing years of their clinical and scientific experience in the search for solutions. Collectively their contributions bring together a wealth of up to date information to pr ... Read more

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This volume provides a comprehensive account of the mostrecent trends in human leukemia, as presented at the NinthWilsede Meeting. Theinternationally renowned contributorsdeal with all different aspects ofthese diseases: As wellas discussing important clinical aspects of leukemia, newinformation on the biological basis of leukemia gainedusingthe methods of molecular genetics, cell and molecularbiology,virology, and immunology is covered. The book showsboth the complexity ofleukemia research, as well as thevalue of basic scientific research in furthering clinicalmedicine and therapy. ... Read more

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This book describes all human leukemia-lymphoma cell lines that have been established and that grow continuously under standardised in vitro conditions. These lines are derived from cells belonging to all the major hematopoietic cell lineages, i.e. B- and T-lymphocytes, natural killer cells, granulocytic cells and megakaryocytic cells. The clinical data, the culture conditions and the major phenotypic features of the cell lines are described with citations. This book is the first book describing human leukemia-lymphoma cell lines and will be of interest to scientists involved in the areas of hematology, oncology, immunology, molecular biology and cytogenetics.Cancer Cell Lines, Volumes 1--3: These 3 volumes provide a comprehensive text on the culture of established cell lines from every type of human cancer. The volumes provide a basic manual and reference resource for every cancer research scientist using human cancer cells. ... Read more

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In March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading."Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and printing.This book was created for medical professionals, students, and members of the general public who want to conduct medical research using the most advanced tools available and spending the least amount of time doing so. ... Read more

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Univ. of Munster, Germany. Presents the rapid progress in the medical understanding of leukemia and the identification of novel therapeutic approaches for the disease. Coverage includes first-hand reports from leading study groups and the latest updates on multicenter trials of new therapies. DNLM: Leukemia--Therapy. ... Read more

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The world of experimental leukaemia research is a miniature of cancer research. Cancer research started from experimental leukaemia/sarcoma research of Ellermann and Bang and Peyton Rous in early 1900s. Experimental leukaemia includes most of important elements of cancer research; both viral and chemical carcinogenesis; most of important oncogenes and suppresser genes and the related cell biology. The author has added only a few sections such as skin carcinogenesis done by Yamagiwa and Berenblum and DNA viruses from outside of experimental leukaemia. By doing this, this book covers most of important topics of modern oncology, except researches done on human cancers. In this book, the author has arranged the chapters to contrast the pioneer works by Peyton Rous, Jacob Furth, and Ludwik Gross, etc, done more than half a century ago and the recent works by molecular biologists.Although the former pathologists provided various experimental materials, faced to severe criticism by contemporary researchers and they had tough hearts to cope with them, molecular biologists solved questions on these materials step by step by disclosing the invisible molecular events as a visible charts, molecular diagrams, or 3-D models just as magicians do. Experimental leukaemia has always afforded the key materials for solution of cancer. In experimental leukaemia, mutations and genetic recombination play an important role. They include ras gene mutations, insertional mutagenesis and gene transduction by retroviruses, recombination among retroviruses, and chromosome translocations. Most of them occur in highly specific genomic sites. However, the reason for the specificity in target sites remained obscure. The author was especially interested in the common target genomic sites for chemical carcinogens and retroviruses. Therefore the common pathway for retroviruses and chemicals became one of the main topics of this book. ... Read more

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This book is an inspiring, often humorist and a very intimate account of being diagnose twice with leukemia. Surviving a bone marrow transplant and a deadly form of pneumonia is only half the battle.Enduring severe Graft versus Host Disease, numerous infections, and encountering a psychotic behavior from a prescription drug with major depression aftermath is all included in this war. Frances finds victory through her positive approach and an enlightened true story with a spiritual angel.She is taught to believe in herself. Learn to forgive and love herself and help others. If you have that, you can conquer anything in this world! ... Read more

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A gentle, positive, candid, and highly recommended memoir
An Angel At My Side: Surviving Leukemia through Love is the powerful, life-affirming testimony of author Frances Schindler, who had been twice diagnosed with leukemia and confronted her tremendous personal battle for recovery with courage, honesty, and humor. Schindler attributes her victory over cancer to faith, an upbeat, optimistic attitude, and the kindness of an angel of her own. This gentle, positive, candid, and highly recommended memoir concludes with a short list of support group resources and alternative therapies in addition to aggressive medical treatment, and is enhanced with a handful of black-and-white photographs. ... Read more

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Papers discuss the controversies on cytogenetic data and provide a detailed review of oncogenes in relation to B-cell disorders. Specific attention is given to researach studies using tumor promoters and biological modifiers in chronic lymphocytic leukemia. Chronic Lymphocytic Leukemia presents important information on topics such as variants of the disease, prolymphocytic leukemia, T-cell leukemias, Richter's syndrome, and B- and T-cell functions. ... Read more